Blood cancer Clinical Trials in Irvine, CA
As of August 2026, 30 paid clinical trials are recruiting for Blood cancer in Irvine, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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30 clinical trials for Blood cancer
·Clear filters·A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma
A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)
Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene
L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance
Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors
A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients
Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms
Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma
Different Types of Massage Therapy to Reduce Anxiety During Chemotherapy Infusion in Patients With Cancer
Aromatherapy Essential Oils to Manage Anxiety and Nausea in Cancer Patients Receiving Infusion in the Ambulatory Setting
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome
Top Research Study Locations in Irvine
Researchers run research studies in Irvine, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| City of Hope at Irvine Lennar | Anatomic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 63 |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Metastatic Malignant Solid Neoplasm, Stage IV Colorectal Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 59 |
| University of California, Irvine | Alopecia Areata, Alzheimer Disease, Amyotrophic Lateral Sclerosis | 34 |
| University of California Irvine | Acute Decompensated Heart Failure, Age-related Macular Degeneration (AMD), Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV) | 19 |
| Kaiser Permanente-Irvine | Breast Cancer, Ovarian Carcinoma, Adenocarcinoma of the Colon | 18 |
| City of Hope Orange County Lennar Foundation Cancer Center | Breast Neoplasms, Multiple Myeloma, Carcinoma, Non-Small-Cell Lung | 11 |
| City of Hope - Orange County Lennar Foundation Cancer Center | Breast Cancer, Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer, Non Small Cell Lung Cancer | 11 |
| Irvine Clinical Research | Alzheimer Disease, Amyloid, Plaque, Amyloid | 10 |
| City of Hope | Advanced Hodgkin Lymphoma, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 7 |
| Chao Family Comprehensive Cancer Center and Ambulatory Care | Endometrial Cancer, Hepatocellular Carcinoma, Advanced Hepatocellular Carcinoma | 7 |
| Beckman Laser Institute and Medical Clinic | Abnormal Vascular Flow, Dermatologic Diseases, Gingivitis | 4 |
| Hoag Memorial Hospital Presbyterian | Prostate Cancer, B7H3, Castration Resistant Metastatic Prostate Cancer | 4 |
| City of Hope - Lennar | Anemia, KRAS G12C-mutated Solid Tumors, Lung Cancer, KRAS, NRAS, HRAS-mutated NSCLC | 3 |
| City of Hope - Lennar Foundation Cancer Center | Breast Cancer, Ductal Carcinoma in Situ, Multiple Myeloma | 3 |
| Hoag Hospital Irvine | Breast Cancer, Breast Cancer Metastatic, Breast Neoplasm | 3 |
| Hoag Memorial Hospital | Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction | 3 |
| Irvine Center for Clinical Research | Alzheimers Disease, Alzheimer's Disease | 3 |
| Susan Samueli Integrative Health Institute | Fibromyalgia, Hypertension, Mild to Moderate Hypertension | 3 |
| UC Irvine | Advanced Adenocarcinoma, Diabetes Mellitus Type 2, Neutropenia | 3 |
| UCI Health - Irvine | Advanced Hepatocellular Carcinoma, Cachexia, Carcinoma, Hepatocellular | 3 |
| Univ of California, Irvine- Gavin Herbert Eye Institute | Amblyopia | 3 |
| University of California | Depression, Anxiety, Heart Diseases, Hypertension | 3 |
| University of California - Irvine Medical Center | Huntington's Disease, Non-muscle Invasive Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ | 3 |
| University of California at Irvine | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| City of Hope Lennar Foundation Cancer Center | Carcinoma, Small Cell Lung, Lung Neoplasms, Small Cell Cancer Of The Lung | 3 |
Active & Upcoming Studies in Irvine (2026)
Recruiting trials in Irvine grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (194 active studies)
- Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma · Phase 1 · City of Hope Medical Center
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
Neurology & pain (24 active studies)
- A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease · Phase 1 · Eli Lilly and Company
- A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease · Phase 1 · Eli Lilly and Company
Diabetes & metabolic (6 active studies)
- HOPE Intervention for Fitness · University of California, Irvine
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Cardiovascular (6 active studies)
- VWCR to Improve Cardiovascular Health and Outcomes Among Cardiac Patients: A Multicenter Randomized Clinical Trial Protocol (Destination Cardiac Rehab Study) · Mayo Clinic
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Mental health & behavior (4 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Eye & vision (3 active studies)
- Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD) · Ray Therapeutics, Inc.
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Vaccines (2 active studies)
- Exercise in Child Health · University of California, Irvine
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Common conditions studied in Irvine
- Breast Cancer (12 active studies)
- Endometrial Cancer (9 active studies)
- Multiple Myeloma (9 active studies)
- Anatomic Stage IV Breast Cancer AJCC v8 (7 active studies)
- Alzheimer Disease (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (6 active studies)
Leading research sponsors in Irvine
- National Cancer Institute (NCI)
- University of California, Irvine
- City of Hope Medical Center
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Irvine?
There are approximately 380 recruiting clinical trials in Irvine, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Irvine pay participants?
Most recruiting trials in Irvine compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Irvine?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Irvine?
The most common conditions under active study in Irvine include Breast Cancer (12), Endometrial Cancer (9), Multiple Myeloma (9), Anatomic Stage IV Breast Cancer AJCC v8 (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Irvine?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Irvine on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Irvine?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Irvine?
Recruiting research sites in Irvine include City of Hope at Irvine Lennar, UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, University of California, Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Irvine right now?
The largest active categories in Irvine are Cancer & tumors (194), Neurology & pain (24), Diabetes & metabolic (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.