Overactive bladder Clinical Trials in Irvine, CA
As of June 2026, 1 paid clinical trial is recruiting for Overactive bladder in Irvine, California. Recruiting Overactive bladder studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Overactive bladder
·Clear filters·↓ Download CSVAbout research studies in Irvine
Irvine has approximately 385 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Irvine
Researchers run research studies in Irvine, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| City of Hope at Irvine Lennar | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 62 |
| UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care | Metastatic Malignant Solid Neoplasm, Stage IV Colorectal Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 55 |
| University of California, Irvine | Alzheimer Disease, Alopecia Areata, Amyotrophic Lateral Sclerosis | 37 |
| Kaiser Permanente-Irvine | Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 22 |
| University of California Irvine | Acute Decompensated Heart Failure, Acute Myeloid Leukemia, Age-related Macular Degeneration (AMD) | 21 |
| City of Hope Orange County Lennar Foundation Cancer Center | Multiple Myeloma, Prostate Cancer, Appendiceal Adenocarcinoma | 9 |
| Irvine Clinical Research | Major Depressive Disorder, Alzheimer Disease, Alzheimer's Disease | 7 |
| City of Hope | Advanced Hodgkin Lymphoma, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 6 |
| Beckman Laser Institute and Medical Clinic | Abnormal Vascular Flow, Dermatologic Diseases, Gingivitis | 4 |
| Chao Family Comprehensive Cancer Center and Ambulatory Care | Endometrial Cancer, Breast Cancer, Cachexia | 4 |
| City of Hope - Orange County Lennar Foundation Cancer Center | Breast Cancer, Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer, Non-small Cell Lung Cancer | 4 |
| Hoag Hospital Irvine | Breast Cancer, Breast Cancer Metastatic, Breast Neoplasm | 4 |
| University of California - Irvine Medical Center | Huntington's Disease, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Pompe Disease | 4 |
| City of Hope - Lennar | Anemia, KRAS G12C-mutated Solid Tumors, Lung Cancer, KRAS, NRAS, HRAS-mutated NSCLC | 3 |
| Hoag Memorial Hospital | Esophageal Cancer, Gastric Cancer (GC), Gastroesophageal Junction | 3 |
| Hoag Memorial Hospital Presbyterian | Cervical Adenocarcinoma, Colorectal Adenocarcinoma, Head and Neck Cancer | 3 |
| Irvine Center for Clinical Research | Alzheimers Disease, Alzheimer's Disease | 3 |
| Kaiser Permanente Southern California | B Cell Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma | 3 |
| Susan Samueli Integrative Health Institute | Fibromyalgia, Hypertension, Mild to Moderate Hypertension | 3 |
| UC Irvine | Advanced Adenocarcinoma, Diabetes Mellitus Type 2, Neutropenia | 3 |
| Univ of California, Irvine- Gavin Herbert Eye Institute | Amblyopia | 3 |
| University of California - Irvine | AAA - Abdominal Aortic Aneurysm, FKRP, FKRP Mutation | 3 |
| University of California at Irvine- Site Number : 840036 | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC), Non-Small Cell Lung Cancer | 2 |
| ATP Clinical Research Inc. | Lewy Body Dementia Psychosis | 2 |
Active & Upcoming Studies in Irvine (2026)
Recruiting trials in Irvine grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (194 active studies)
- Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 · Phase 2 · City of Hope Medical Center
- Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma · Phase 2 · City of Hope Medical Center
Neurology & pain (24 active studies)
- Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY) · Phase 3 · Alexandre P. Joosten
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
Diabetes & metabolic (7 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass · Boston Scientific Corporation
Cardiovascular (6 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258) · Phase 3 · Reprieve Cardiovascular, Inc
Eye & vision (5 active studies)
- Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD) · Ray Therapeutics, Inc.
- A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease · Phase 3 · AbbVie
Mental health & behavior (3 active studies)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
- Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Patients · University of California, Irvine
Vaccines (2 active studies)
- Exercise in Child Health · University of California, Irvine
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Common conditions studied in Irvine
- Breast Cancer (13 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Endometrial Cancer (8 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Multiple Myeloma (8 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Stage IV Lung Cancer AJCC v8 (8 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Anatomic Stage IV Breast Cancer AJCC v8 (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Ovarian Cancer (7 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
Leading research sponsors in Irvine
- National Cancer Institute (NCI)
- University of California, Irvine
- City of Hope Medical Center
- NRG Oncology
- AstraZeneca
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Irvine. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Irvine
Hipa.ai aggregates every recruiting study in Irvine from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Irvine?
There are approximately 385 recruiting clinical trials in Irvine, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Irvine pay participants?
Most recruiting trials in Irvine compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Irvine?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Irvine?
The most common conditions under active study in Irvine include Breast Cancer (13), Endometrial Cancer (8), Multiple Myeloma (8), Stage IV Lung Cancer AJCC v8 (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Irvine?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Irvine on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Irvine?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Irvine?
Recruiting research sites in Irvine include City of Hope at Irvine Lennar, UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, University of California, Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Irvine right now?
The largest active categories in Irvine are Cancer & tumors (194), Neurology & pain (24), Diabetes & metabolic (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.