Paid Clinical Trials in Jacksonville, FL
As of June 2026, 957 paid clinical trials are recruiting in Jacksonville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Jacksonville offers studies at sites including Mayo Clinic in Florida for conditions such as Malignant Solid Neoplasm, Breast Cancer, Heart Failure, Obesity. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Jacksonville
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·Clear filters·↓ Download CSVAbout research studies in Jacksonville
Jacksonville has approximately 957 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Jacksonville
Researchers run research studies in Jacksonville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic in Florida | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Anatomic Stage III Breast Cancer AJCC v8 | 188 |
| Mayo Clinic | Amyotrophic Lateral Sclerosis, Colorectal Cancer, Advanced Solid Tumor | 80 |
| Mayo Clinic Florida | Amyotrophic Lateral Sclerosis, Advanced Melanoma, Breast Neoplasms | 77 |
| Mayo Clinic Jacksonville | Amyotrophic Lateral Sclerosis (ALS), Non Small Cell Lung Cancer, Prostate Cancer | 44 |
| Nemours Children's Clinic-Jacksonville | Malignant Solid Neoplasm, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 30 |
| Jacksonville Center for Clinical Research | Heart Failure, Obesity, Cardiovascular Disease | 22 |
| Baptist MD Anderson Cancer Center | Breast Cancer, Advanced Melanoma, Anatomic Stage I Breast Cancer AJCC v8 | 20 |
| Mayo Clinic - Jacksonville | Breast Cancer, Metastatic Breast Cancer, Acute Lymphoblastic Leukemia (ALL) | 14 |
| University of Florida | Coronary Artery Disease, Age-related Cognitive Decline, Allergies | 14 |
| Cancer Specialists of North Florida | Acinar Cell Carcinoma, Advanced Cancer, Cancer | 12 |
| Brooks Rehabilitation | Spinal Cord Injuries, Spinal Cord Injury, Stroke | 9 |
| Mayo Clinic - Florida | Epilepsy, Epilepsy (Treatment Refractory), Astrocytoma, Grade IV | 9 |
| Nemours Children's Health | Asthma (Diagnosis), Autosomal Dominant Hypocalcemia Type 1 (ADH1), Child | 9 |
| Baptist Health Research Institute | Acute Ischemic Stroke, Alzheimer Disease, Aneurysm, Intracranial | 8 |
| University of Florida Jacksonville | Coronary Artery Disease, AV Block, Acute Stroke | 8 |
| Ascension St. Vincent's | Atrial Fibrillation, Brain Tumor, Brain Tumor - Metastatic | 7 |
| UF Health Jacksonville | Atrial Fibrillation, Autonomic State, Diabetes Mellitus, Type 2 | 7 |
| Baptist Medical Center Jacksonville | Intracranial Aneurysm, Chronic Subdural Hematoma, Intracranial Atherosclerotic Stenosis (ICAS) | 6 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Breast Neoplasms, Gastrointestinal Neoplasms | 6 |
| Nemours Children's Clinic | Cystic Fibrosis, Amblyopia, Cystic Fibrosis Pulmonary Exacerbation | 6 |
| University of Florida Health Jacksonville | Acute Gout Flare, Acute Ischemic Stroke, Arthritis | 6 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Cerebral Amyloid Angiopathy | 5 |
| Clinical Neuroscience Solutions, Inc. | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 5 |
| Mayo Clinic Cancer Center | Acute Myeloid Leukemia, CRC, Colorectal Cancer | 5 |
| Mayo Clinic Hospital | Fractures, Glioblastoma, Glioblastoma (GBM) | 5 |
Active & Upcoming Studies in Jacksonville (2026)
Recruiting trials in Jacksonville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (332 active studies)
Cardiovascular (68 active studies)
Neurology & pain (54 active studies)
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up · Epiminder America, Inc.
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
Diabetes & metabolic (41 active studies)
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
Mental health & behavior (14 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder · Phase 3 · Cybin IRL Limited
HIV / STI (7 active studies)
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System · University of Florida
- Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV · Phase 1, Phase 2 · National Institute of Allergy and Infectious Diseases (NIAID)
Pediatric (7 active studies)
Eye & vision (6 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease · Phase 2 · Bausch & Lomb Incorporated
Vaccines (3 active studies)
Common conditions studied in Jacksonville
- Malignant Solid Neoplasm (21 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (19 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (16 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Obesity (14 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Prostate Cancer (14 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Hematopoietic and Lymphatic System Neoplasm (13 active studies). Recruiting Hematopoietic and Lymphatic System Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- National Cancer Institute (NCI)
- University of Florida
- Eli Lilly and Company
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Jacksonville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Jacksonville
Hipa.ai aggregates every recruiting study in Jacksonville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 957 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Malignant Solid Neoplasm (21), Breast Cancer (19), Heart Failure (16), Obesity (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (332), Cardiovascular (68), Neurology & pain (54). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.