Solid tumor Clinical Trials in La Jolla, CA
As of August 2026, 29 paid clinical trials are recruiting for Solid tumor in La Jolla, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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29 clinical trials for Solid tumor
·Clear filters·The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
A Study of YL201 in Patients With Advanced Solid Tumors
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies
A Study Evaluating OBI-902 in Participants With Advanced Solid Tumors
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial
Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas
Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors
Top Research Study Locations in La Jolla
Researchers run research studies in La Jolla, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UC San Diego Moores Cancer Center | Stage IV Lung Cancer AJCC v8, Metastatic Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8 | 83 |
| University of California San Diego | Amyotrophic Lateral Sclerosis, Cancer, Colorectal Cancer | 58 |
| University of California, San Diego | Prostate Cancer, Breast Cancer, Danon Disease | 51 |
| UC San Diego | Aortic Aneurysm, Abdominal, Becker Muscular Dystrophy, COVID -19 | 16 |
| Scripps Health | Aortic Insufficiency, Aortic Regurgitation, Aortic Valve Insufficiency | 13 |
| UCSD Moores Cancer Center | Cancer, CRC, Colon Cancer | 12 |
| UC San Diego Health | Heart Failure, Ventricular Fibrillation, Central Nervous System Lymphoma | 9 |
| Altman Clinical and Translational Research Institute | Chronic Low-back Pain, Complex Regional Pain Syndrome, Healthy Participants Study | 6 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Breast Cancer | 6 |
| UCSD | Advanced/Metastatic Solid Tumors, Bipolar Disorder, Colorectal Cancer | 6 |
| University of California San Diego Moores Cancer Center | Advanced Solid Tumor, Cervical Cancer, Metastatic Castration-resistant Prostate Cancer | 6 |
| Scripps Clinic Torrey Pines | Carcinoma, Hepatocellular, Colitis, Ulcerative, Colorectal Cancer Metastatic | 5 |
| Scripps Green Hospital | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Acute Myeloid Leukemia Refractory | 5 |
| Scripps Memorial Hospital | Acute Decompensated Heart Failure, Coronary Arterial Disease (CAD), Heart Failure - NYHA II - IV | 5 |
| Scripps Translational Science Institute | Coronary Artery Disease, Healthy, Heart Diseases | 5 |
| University of California San Diego Medical Center | Alzheimers Disease, Alzheimers Disease, Familial, Dementia | 5 |
| Kadima Neuropsychiatry Institute | Depression, Depressive Disorder, Treatment-Resistant, Generalized Anxiety Disorder | 4 |
| Moores Cancer Center | Neoplasm Metastasis, Advanced Breast Cancer, Advanced Ovarian Cancer | 4 |
| Shiley Center for Orthopaedic Research and Education at Scripps Clinic | Adult Spinal Deformity, Kyphosis, Scoliosis | 4 |
| University of California at San Diego | Carcinoma, Non-small-Cell Lung, Hemolytic Disease of the Fetus and Newborn, Metastatic Castration-resistant Prostatic Neoplasms | 4 |
| University of California, San Diego Moores Cancer Center | Basal Cell Carcinoma, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer | 4 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Neoplasms, Prostate, Tumours, Gynecological | 3 |
| Kaizen Brain Center | Agitation, Alzheimer Disease, Chronic Migraine | 3 |
| Scripps Memorial Hospital La Jolla | Aortic Valve Disease Mixed, Aortic Valve Regurgitation, Heart Failure | 3 |
| UC San Diego Altman Clinical and Translational Research Institute | Anorexia Nervosa, Cardiometabolic Syndrome, Drug Interactions | 3 |
Active & Upcoming Studies in La Jolla (2026)
Recruiting trials in La Jolla grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (185 active studies)
- Neu Direction: Testing the Efficacy of Adding HER Inhibition to Standard of Care in Metastatic MLH1-low Endocrine-resistant ER+/HER2- Breast Cancer · Phase 2 · University of California, San Diego
- Signatera Assessment in Early-Stage Endometrial Cancer · Natera, Inc.
Neurology & pain (44 active studies)
- Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery · University of California, San Diego
- Digital Lifestyle Coaching for Alzheimer's Disease Prevention in APOE4 Carriers · Scripps Translational Science Institute
Cardiovascular (31 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial · National Bureau of Economic Research, Inc.
Diabetes & metabolic (22 active studies)
- Time Restricted Eating in Patients With Microalbuminuria · Phase 1 · University of California, San Diego
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Mental health & behavior (13 active studies)
- Frontal Gamma Coherence Neurofeedback for Patients With Schizophrenia · BioSignal Solutions LLC
- RE104 Safety and Efficacy Study in Generalized Anxiety Disorder · Phase 2 · Reunion Neuroscience Inc
HIV / STI (8 active studies)
- Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy · International Maternal Pediatric Adolescent AIDS Clinical Trials Group
- An mHealth Intervention to Improve HIV Prevention Service Engagement Among People Who Use Drugs · University of California, San Diego
Eye & vision (8 active studies)
- Study of Serine Supplementation to Protect Vision in MacTel · Phase 3 · The Lowy Medical Research Institute Limited
- The Effectiveness of Systane PRO Preservative Free Verses Blink Triple Care Preservative Free · Phase 4 · Gordon Schanzlin New Vision
Vaccines (4 active studies)
- Preparedness Through Respiratory Virus Epidemiology and Community Engagement · University of California, San Diego
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
Pediatric (2 active studies)
- Flow and Grow - The Ideal Time to Wean CPAP Off In Extremely Low Birth Weight Infants · University of California, San Diego
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in La Jolla
- Breast Cancer (14 active studies)
- Prostate Cancer (12 active studies)
- Colorectal Cancer (11 active studies)
- Ovarian Cancer (11 active studies)
- Advanced Solid Tumor (10 active studies)
- Heart Failure (10 active studies)
Leading research sponsors in La Jolla
- University of California, San Diego
- National Cancer Institute (NCI)
- AstraZeneca
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in La Jolla?
There are approximately 534 recruiting clinical trials in La Jolla, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in La Jolla pay participants?
Most recruiting trials in La Jolla compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in La Jolla?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in La Jolla?
The most common conditions under active study in La Jolla include Breast Cancer (14), Prostate Cancer (12), Colorectal Cancer (11), Ovarian Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in La Jolla?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in La Jolla on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in La Jolla?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in La Jolla?
Recruiting research sites in La Jolla include UC San Diego Moores Cancer Center, University of California San Diego, University of California, San Diego, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in La Jolla right now?
The largest active categories in La Jolla are Cancer & tumors (185), Neurology & pain (44), Cardiovascular (31). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.