Clinical Trials at UC San Diego Moores Cancer Center

As of August 2026, 82 paid clinical trials are recruiting at UC San Diego Moores Cancer Center in La Jolla, California. Active studies at this site cover conditions such as Breast Cancer, Prostate Cancer and Colorectal Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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82 clinical trials at UC San Diego Moores Cancer Center

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Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

for Urothelial Cancer

Drug: PF-08634404

Sites in La Jolla, San Diego +131 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07421700·Phase 1, Phase 2·Recruiting·Listed Feb 2026

Apply to this trial

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Cancer

Drug: daraxonrasib

Sites in La Jolla, Los Angeles +33 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07252232·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

for Non-small Cell Carcinoma

Sites in La Jolla, San Diego +216 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07144280·Phase 3·Recruiting·Listed Aug 2025

Apply to this trial

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for Breast Cancer

Sites in La Jolla, San Marcos +170 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06492616·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

Drug: ponsegromab

Sites in La Jolla, San Diego +81 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting·Listed May 2025

Apply to this trial

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

Sites in La Jolla, Newport Beach +40 more locations

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

Sites in La Jolla, Duarte +41 more locations

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

Sites in La Jolla, Duarte +35 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

Sites in La Jolla, Orange +42 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024

Apply to this trial

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

Sites in La Jolla, San Diego +46 more locations

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting·Listed Feb 2021

Apply to this trial

Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

Sites in La Jolla, Oceanside +42 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

Sites in La Jolla, Los Angeles +30 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Nivolumab

Sites in La Jolla, Los Angeles +27 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in La Jolla, San Diego +56 more locations

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting·Listed Jun 2024

Apply to this trial

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for Breast Cancer

Drug: Giredestrant

Sites in La Jolla, San Diego +24 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07100106·Phase 1, Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

Sites in La Jolla, Duarte +20 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

for Breast Cancer, Metastatic

Sites in La Jolla, Orange +21 more locations

Sponsor: ALX Oncology Inc.

Sex: All·Age: 18+

Code: NCT07007559·Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for Solid Tumor

Sites in La Jolla +10 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06619587·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for HR+ Breast Cancer

Sites in La Jolla, Duarte +16 more locations

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07029399·Phase 1·Recruiting·Listed Jun 2025

Apply to this trial

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for Advanced Solid Tumor

Drug: NXP900

Sites in La Jolla +12 more locations

Sponsor: Nuvectis Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05873686·Phase 1·Recruiting·Listed May 2023

Apply to this trial

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

Sites in La Jolla, Irvine +22 more locations

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

for Hepatocellular Carcinoma

Sites in La Jolla, Beverly Hills +10 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 18+

Code: NCT05733598·Phase 2·Recruiting·Listed Feb 2023

Apply to this trial

Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

for Endometrial Cancer

Sites in La Jolla, San Francisco +16 more locations

Sponsor: Faeth Therapeutics

Sex: Female·Age: 18+

Code: NCT06463028·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

for Gastrointestinal Stromal Tumor (GIST)

Sites in La Jolla +9 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06630234·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

for Relapsed Multiple Myeloma

Sites in La Jolla, Stanford +10 more locations

Sponsor: Opna Bio LLC

Sex: All·Age: 18+

Code: NCT06433947·Phase 1·Recruiting·Listed May 2024

Apply to this trial

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

for Non-Small Cell Lung Cancer

Sites in La Jolla +4 more locations

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT07216105·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

for Melanoma

1 location in La Jolla

Sponsor: Replimune, Inc.

Sex: All·Age: 18+

Code: NCT06887348·Recruiting·Listed Mar 2025

Apply to this trial

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

for Solid Tumor, Adult

Sites in La Jolla, Stanford +1 more location

Sponsor: BioEclipse Therapeutics

Sex: All·Age: 18+

Code: NCT04282044·Phase 1·Recruiting·Listed Feb 2020

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in La Jolla, San Diego +628 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in La Jolla, San Diego +913 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

Apply to this trial

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

Sites in La Jolla, Torrance +444 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015

Apply to this trial

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in La Jolla, San Diego +591 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in La Jolla, San Diego +653 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

Apply to this trial

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

Sites in La Jolla, San Diego +305 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

Sites in La Jolla, San Diego +380 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017

Apply to this trial

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in La Jolla, San Diego +442 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023

Apply to this trial

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

Sites in La Jolla, San Diego +276 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020

Apply to this trial

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

Sites in La Jolla, Irvine +324 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06958328·Phase 3·Recruiting·Listed May 2025

Apply to this trial

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

Sites in La Jolla, San Diego +406 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in La Jolla, Irvine +206 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT07097142·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

Common conditions studied in La Jolla

Breast Cancer (14 active studies)
Prostate Cancer (12 active studies)
Colorectal Cancer (11 active studies)
Ovarian Cancer (11 active studies)
Advanced Solid Tumor (10 active studies)
Heart Failure (10 active studies)

Leading research sponsors in La Jolla

University of California, San Diego
National Cancer Institute (NCI)
AstraZeneca
Eli Lilly and Company
NRG Oncology

Frequently asked questions

How many paid clinical trials are currently recruiting in La Jolla?

There are approximately 532 recruiting clinical trials in La Jolla, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in La Jolla pay participants?

Most recruiting trials in La Jolla compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in La Jolla?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in La Jolla?

The most common conditions under active study in La Jolla include Breast Cancer (14), Prostate Cancer (12), Colorectal Cancer (11), Ovarian Cancer (11), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in La Jolla?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in La Jolla on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in La Jolla?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in La Jolla?

Recruiting research sites in La Jolla include UC San Diego Moores Cancer Center, University of California San Diego, University of California, San Diego, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in La Jolla right now?

The largest active categories in La Jolla are Cancer & tumors (185), Neurology & pain (44), Cardiovascular (31). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

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Related healthcare resources in California

Latest California clinical trials research report

Trials by condition in La Jolla

Breast Cancer· 14 Prostate Cancer· 12 Colorectal Cancer· 11 Ovarian Cancer· 11 Heart Failure· 10 Head and Neck Squamous Cell Carcinoma· 7