Colorectal cancer Clinical Trials in Los Angeles, CA
As of July 2026, 38 paid clinical trials are recruiting for Colorectal cancer in Los Angeles, California. Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Los Angeles
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38 clinical trials for Colorectal cancer
·Clear filters·↓ Download CSVA Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas
A Study of MGC026 in Participants With Advanced Solid Tumors
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
CoGENES Randomized Controlled Trial (RCT)
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care
Personalized Health Self-Management Training for Colorectal Cancer Survivors
Confronting Cancer as a Community
Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps
ColoCare Study - Colorectal Cancer Cohort
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
About research studies in Los Angeles
Los Angeles has approximately 2,089 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Los Angeles
Researchers run research studies in Los Angeles, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cedars-Sinai Medical Center | Breast Cancer, Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8 | 238 |
| Children's Hospital Los Angeles | Neuroblastoma, Acute Myeloid Leukemia, Anesthesia | 137 |
| University of California, Los Angeles | Alzheimer Disease, Depression, Focal Epilepsy | 113 |
| University of Southern California | Acute Pancreatitis, Amyotrophic Lateral Sclerosis, Breast Cancer | 102 |
| USC / Norris Comprehensive Cancer Center | Malignant Solid Neoplasm, Breast Carcinoma, Hematopoietic and Lymphatic System Neoplasm | 80 |
| Cedars Sinai Medical Center | Anxiety, Aortic Dissection, Crohn's Disease | 74 |
| UCLA / Jonsson Comprehensive Cancer Center | Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8, Prostate Adenocarcinoma | 70 |
| University of California Los Angeles | Parkinson Disease, Bladder Cancer, Breast Cancer | 70 |
| Los Angeles General Medical Center | Metastatic Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8, Unresectable Malignant Solid Neoplasm | 65 |
| USC Norris Comprehensive Cancer Center | Colorectal Cancer, Endometrial Cancer, NSCLC | 56 |
| UCLA | Bladder Cancer, Colorectal Cancer, Type2diabetes | 54 |
| Kaiser Permanente Los Angeles Medical Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Intracerebral Hemorrhage | 48 |
| Children's Hospital of Los Angeles | Acute Lymphoblastic Leukemia, Cystic Fibrosis, Von Willebrand Disease (VWD) | 39 |
| Valkyrie Clinical Trials | Multiple Myeloma, Solid Tumors, Breast Cancer | 35 |
| Ronald Reagan UCLA Medical Center | Ischemic Stroke, Stroke, Esophageal Adenocarcinoma | 28 |
| USC/Norris Comprehensive Cancer Center | Breast Neoplasms, Bladder Cancer, Breast Cancer | 24 |
| UCLA Medical Center | Colorectal Cancer, CRC, Cancer | 21 |
| Kaiser Permanente West Los Angeles | Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 19 |
| Keck Medicine of USC Koreatown | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 18 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Non-alcoholic Fatty Liver Disease, Breast Neoplasms | 14 |
| David Geffen School of Medicine at UCLA | Developmental and Epileptic Encephalopathy, Candidemia, Candidiasis, Invasive | 14 |
| Keck Hospital of USC | Advanced Hepatocellular Carcinoma, Advanced or Metastatic Solid Tumors, Airway Disease | 14 |
| University of California, Los Angeles (UCLA) | Metastatic Cancer, Adamantinomatous Craniopharyngioma, Adenosine Deaminase Severe Combined Immune Deficiency | 14 |
| Mattel Children's Hospital UCLA | Malignant Solid Neoplasm, Ganglioneuroblastoma, Nodular, Hematopoietic and Lymphatic System Neoplasm | 13 |
| UCLA Health | Adult Growth Hormone Deficiency, Cancer, Chronic Disease | 13 |
Active & Upcoming Studies in Los Angeles (2026)
Recruiting trials in Los Angeles grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (673 active studies)
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer · Phase 2 · Jonsson Comprehensive Cancer Center
- A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer · Jonsson Comprehensive Cancer Center
Neurology & pain (123 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- Measuring Pelvic Floor Muscle Fitness Before and After Treatment · University of California, Los Angeles
Cardiovascular (98 active studies)
- Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress · Duke University
- PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis · Phase 3 · Duke University
Diabetes & metabolic (66 active studies)
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
- A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
Mental health & behavior (64 active studies)
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
- Group PACBT for Depression · Phase 2 · University of California, Los Angeles
Pediatric (37 active studies)
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
- Early Re-Initiation of Semaglutide Post Sleeve Gastrectomy in Youth · Phase 3 · Children's Hospital Los Angeles
HIV / STI (25 active studies)
- Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization · Keck School of Medicine of USC
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
Eye & vision (13 active studies)
- Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension · Stanford University
- This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to Study CDE and Ultrasound Time During Cataract Removal · Nicole Fram M.D.
Vaccines (10 active studies)
Common conditions studied in Los Angeles
- Breast Cancer (44 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Colorectal Cancer (30 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Prostate Cancer (28 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Cancer (22 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ovarian Cancer (22 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Heart Failure (21 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
Leading research sponsors in Los Angeles
- University of California, Los Angeles
- University of Southern California
- Cedars-Sinai Medical Center
- Jonsson Comprehensive Cancer Center
- National Cancer Institute (NCI)
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Los Angeles. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Los Angeles
Hipa.ai aggregates every recruiting study in Los Angeles from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Los Angeles?
There are approximately 2,089 recruiting clinical trials in Los Angeles, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Los Angeles pay participants?
Most recruiting trials in Los Angeles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Los Angeles?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Los Angeles?
The most common conditions under active study in Los Angeles include Breast Cancer (44), Colorectal Cancer (30), Prostate Cancer (28), Cancer (22), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Los Angeles?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Los Angeles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Los Angeles?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Los Angeles?
Recruiting research sites in Los Angeles include Cedars-Sinai Medical Center, Children's Hospital Los Angeles, University of California, Los Angeles, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Los Angeles right now?
The largest active categories in Los Angeles are Cancer & tumors (673), Neurology & pain (123), Cardiovascular (98). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.