Paid Clinical Trials in Newport Beach, CA
As of June 2026, 217 paid clinical trials are recruiting in Newport Beach, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Newport Beach offers studies at sites including Hoag Memorial Hospital Presbyterian for conditions such as Breast Cancer, Breast Neoplasms, Advanced Solid Tumor, Head and Neck Squamous Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Newport Beach
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·Clear filters·↓ Download CSVAbout research studies in Newport Beach
Newport Beach has approximately 217 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Newport Beach
Researchers run research studies in Newport Beach, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Hoag Memorial Hospital Presbyterian | Breast Cancer, Advanced Solid Tumor, Advanced Breast Cancer | 45 |
| USC Norris Oncology/Hematology-Newport Beach | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 25 |
| Hoag Memorial Hospital | Advanced Solid Tumor, Head and Neck Squamous Cell Carcinoma, Advanced Solid Tumors | 10 |
| City of Hope Newport Beach | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 7 |
| Eye Research Foundation | Dry Eye Disease (DED), Ocular Hypertension, Glaucoma, Open-Angle | 7 |
| City of Hope at Newport Beach Fashion Island | Lung Non-Small Cell Carcinoma, Metastatic Pancreatic Adenocarcinoma, Multiple Myeloma | 5 |
| NewportNativeMD, Inc. | Asthma, Interstitial Lung Disease, Moderate to Severe Chronic Obstructive Pulmonary Disease | 5 |
| Hoag Hospital | Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder), Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder) | 4 |
| Hoag Hospital Newport Beach | Anaplastic Lymphoma Kinase-positive, Atrial Fibrillation, Crohn's Disease | 4 |
| Hoag | Benign Liver Tumor, Genetic Predisposition, Liver Neoplasms | 3 |
| Hoag Family Cancer Institute | Advanced Metastatic Castration Resistant Prostate Cancer, Advanced or Metastatic Solid Tumors, Biliary Tract Cancer | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Hoag Gynecologic Oncology | Cervical Cancer, Endometrioid Ovarian Cancer, Fallopian Tube Cancer | 2 |
| Hoag Memorial Hospital Presbyterian;Hoag Center for Research and Education | Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 2 |
| Newport Native MD, Inc. | COPD, Hypersensitivity Pneumonitis, Interstitial Lung Disease | 2 |
| Newport Therapeutics | Degenerative Disc Disease, Osteoarthritis, Knee | 2 |
| Radin Cardiovascular Medical Group | Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 2 |
| USC Norris Cancer Center | Adenocarcinoma, Pancreatic Ductal, Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer | 2 |
| Autobahn Site #117 | Major Depressive Disorder | 1 |
| CREST Site 05 | Open Angle Glaucoma | 1 |
| CREST-XT Site 05 | Open-angle Glaucoma (OAG) | 1 |
| Clinical Study Site | Non-Small Cell Lung Cancer | 1 |
| Crinetics Study Site | Neuroendocrine Neoplasm, Neuroendocrine Tumors, SST2-positive Neuroendocrine Neoplasms | 1 |
| CureDuchenne | Becker Muscular Dystrophy, Duchenne Muscular Dystrophy | 1 |
| Digestive Health Institute | Crohn's Disease, Ulcerative Colitis | 1 |
Active & Upcoming Studies in Newport Beach (2026)
Recruiting trials in Newport Beach grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (102 active studies)
- Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial · Phase 2 · City of Hope Medical Center
- Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung · Phase 3 · Vergent Bioscience, Inc.
Eye & vision (13 active studies)
- A Clinical Study Evaluating Licaminlimab for Dry Eye Disease · Phase 2, Phase 3 · Oculis
- SYSTANE® PRO vs. MIEBO™ in Dry Eye Disease · Phase 4 · Indiana University
Cardiovascular (11 active studies)
- Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention · Phase 4 · Duke University
- Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity · Phase 3 · Amgen
Neurology & pain (7 active studies)
Diabetes & metabolic (5 active studies)
- A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study) · Aqua Medical, Inc.
- Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity · Phase 3 · Amgen
Vaccines (1 active study)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
Common conditions studied in Newport Beach
- Breast Cancer (10 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Breast Neoplasms (6 active studies). Recruiting Breast Neoplasms studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Solid Tumor (5 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cancer (5 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Head and Neck Squamous Cell Carcinoma (5 active studies). Recruiting Head and Neck Squamous Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Non-small Cell Lung Cancer (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
Leading research sponsors in Newport Beach
- AstraZeneca
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- City of Hope Medical Center
- Hoffmann-La Roche
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Newport Beach. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Newport Beach
Hipa.ai aggregates every recruiting study in Newport Beach from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Newport Beach?
There are approximately 217 recruiting clinical trials in Newport Beach, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Newport Beach pay participants?
Most recruiting trials in Newport Beach compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Newport Beach?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Newport Beach?
The most common conditions under active study in Newport Beach include Breast Cancer (10), Breast Neoplasms (6), Advanced Solid Tumor (5), Cancer (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Newport Beach?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Newport Beach on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Newport Beach?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Newport Beach?
Recruiting research sites in Newport Beach include Hoag Memorial Hospital Presbyterian, USC Norris Oncology/Hematology-Newport Beach, Hoag Memorial Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Newport Beach right now?
The largest active categories in Newport Beach are Cancer & tumors (102), Eye & vision (13), Cardiovascular (11). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.