Oncology Clinical Trials in Newport Beach, CA
As of August 2026, 56 paid clinical trials are recruiting for Oncology in Newport Beach, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
Newly added in Newport Beach
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
57 clinical trials for Oncology
·Clear filters·A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer
SLV-154 Treatment of Advanced Cancers
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
A Phase 1 Study of LNCB74 in Advanced Solid Tumors
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
IKS014 in Advanced Solid Tumors That Express HER2
A Study of KK2269 in Adult Participants With Solid Tumors
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Pancreatic Cancer Early Detection Consortium
Top Research Study Locations in Newport Beach
Researchers run research studies in Newport Beach, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Hoag Memorial Hospital Presbyterian | Advanced Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer | 51 |
| USC Norris Oncology/Hematology-Newport Beach | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 15 |
| Hoag Memorial Hospital | Type 1 Diabetes, Advanced Solid Tumor, Advanced Solid Tumors | 10 |
| NewportNativeMD, Inc. | Asthma, Diffuse Cutaneous Systemic Sclerosis, Interstitial Lung Disease | 7 |
| Eye Research Foundation | Dry Eye Disease (DED), Macular Edema, Moderate to Severe Glabellar Lines | 7 |
| City of Hope Newport Beach | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 6 |
| Hoag Family Cancer Institute | Advanced Metastatic Castration Resistant Prostate Cancer, Advanced NET of GI Origin, Advanced or Metastatic Solid Tumors | 6 |
| City of Hope at Newport Beach Fashion Island | Lung Non-Small Cell Carcinoma, Metastatic Pancreatic Adenocarcinoma, Multiple Myeloma | 5 |
| Hoag | Benign Liver Tumor, Genetic Predisposition, Liver Neoplasms | 5 |
| Hoag Hospital | Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder), Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder) | 4 |
| Hoag Hospital Newport Beach | Anaplastic Lymphoma Kinase-positive, Crohn's Disease, Non-small Cell Lung Cancer | 3 |
| Radin Cardiovascular Medical Group | Atrial Fibrillation (AF), Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| GSK Investigational Site | Asthma, Pulmonary Disease, Chronic Obstructive | 2 |
| Hoag Gynecologic Oncology | Cervical Cancer, Endometrioid Ovarian Cancer, Fallopian Tube Cancer | 2 |
| Hoag Memorial Hospital Presbyterian;Hoag Center for Research and Education | Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 2 |
| University Dermatology Trials | Dermatitis Atopic | 2 |
| CREST-XT | Open-angle Glaucoma (OAG) | 1 |
| California Orbital Consultants | Non-Arteritic Anterior Ischemic Optic Neuropathy | 1 |
| Crinetics Study Site | Neuroendocrine Neoplasm, Neuroendocrine Tumors, SST2-positive Neuroendocrine Neoplasms | 1 |
| Donald S Mowlds, MD A Professional Corporation | Capsular Contracture Associated With Breast Implant, Capsular Contracture Grade III, Capsular Contracture Grade IV | 1 |
| Eye Research Foundation Inc. | Glaucoma, Open-Angle, Ocular Hypertension | 1 |
| Eye research foundation, Inc. | Ocular Hypertension (OH), Primary Open Angle Glaucoma (POAG) | 1 |
| Feinerman Vision Center | Cataract, Posterior Capsule Opacification, Presbyopia | 1 |
| Galderma Investigational | Atopic Dermatitis | 1 |
Active & Upcoming Studies in Newport Beach (2026)
Recruiting trials in Newport Beach grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (81 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Study of Oral MRT-2359 With Apalutamide in Prostate Cancer · Phase 2 · Monte Rosa Therapeutics, Inc
Cardiovascular (10 active studies)
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation · Phase 3 · Regeneron Pharmaceuticals
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
Eye & vision (10 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
Diabetes & metabolic (7 active studies)
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
- A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study) · Aqua Medical, Inc.
Neurology & pain (6 active studies)
Vaccines (1 active study)
- Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. · Phase 2 · Vasomune Therapeutics, Inc.
Mental health & behavior (1 active study)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
Pediatric (1 active study)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Common conditions studied in Newport Beach
- Breast Cancer (6 active studies)
- Breast Neoplasms (6 active studies)
- Advanced Solid Tumor (5 active studies)
- Asthma (5 active studies)
- Non-small Cell Lung Cancer (5 active studies)
- Non Small Cell Lung Cancer (4 active studies)
Leading research sponsors in Newport Beach
- AstraZeneca
- National Cancer Institute (NCI)
- City of Hope Medical Center
- SWOG Cancer Research Network
- AbbVie
Frequently asked questions
How many paid clinical trials are currently recruiting in Newport Beach?
There are approximately 186 recruiting clinical trials in Newport Beach, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Newport Beach pay participants?
Most recruiting trials in Newport Beach compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Newport Beach?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Newport Beach?
The most common conditions under active study in Newport Beach include Breast Cancer (6), Breast Neoplasms (6), Advanced Solid Tumor (5), Asthma (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Newport Beach?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Newport Beach on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Newport Beach?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Newport Beach?
Recruiting research sites in Newport Beach include Hoag Memorial Hospital Presbyterian, USC Norris Oncology/Hematology-Newport Beach, Hoag Memorial Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Newport Beach right now?
The largest active categories in Newport Beach are Cancer & tumors (81), Cardiovascular (10), Eye & vision (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.