Nerve Block for Severe Abdominal Pain in the Emergency Department
for Erector Spinae Plane Block
1 location in Orange
Sponsor: University of California, Irvine
Sex: All·Age: 18+
Code: NCT07826936·EARLY_Phase 1·Recruiting·Listed Sep 17, 2026
Paid Clinical Trials in Orange, CA
As of September 2026, 516 paid clinical trials are recruiting in Orange, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Orange offers studies at sites including Children's Hospital of Orange County for conditions such as Breast Cancer, Ovarian Cancer, Acute Myeloid Leukemia, Hepatocellular Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Orange
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Top Research Study Locations in Orange
Researchers run research studies in Orange, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Children's Hospital of Orange County | B Acute Lymphoblastic Leukemia, Neuroblastoma, Recurrent Malignant Solid Neoplasm | 68 |
| UC Irvine Health/Chao Family Comprehensive Cancer Center | Stage IV Colorectal Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Solid Neoplasm | 62 |
| University of California Irvine | Amyotrophic Lateral Sclerosis, Anticoagulants, Carcinoma, Non-Small-Cell Lung | 27 |
| Chao Family Comprehensive Cancer Center, University of California, Irvine | Glioma, Hepatocellular Carcinoma, Pancreatic Cancer | 20 |
| University of California Irvine Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 20 |
| University of California, Irvine | Myasthenia Gravis, Parkinson Disease, Acute Myeloid Leukemia (AML) | 17 |
| UC Irvine Health | Multiple Myeloma, B-cell Malignancy, Cachexia | 13 |
| UC Irvine Medical Center | Advanced Metastatic Castration Resistant Prostate Cancer, Atrial Fibrillation, Autosomal Dominant Polycystic Kidney Disease | 12 |
| NRC Research Institute | Bipolar Disorder, Bipolar I Disorder, Bipolar Depression | 10 |
| ATP Clinical Research | Bipolar Disorder, Alzheimer's Disease, Bipolar Depression | 9 |
| Chao Family Comprehensive Cancer Center University of California, Irvine | Melanoma (Skin), Cervical Cancer, Chronic Myeloid Leukemia | 8 |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| University of California, Irvine Medical Center | Cancer, Lung, Cardiovascular Diseases, Colorectal Cancer; Lung Cancer | 8 |
| Children's Hospital Orange County | ALL, AML, Acute Undifferentiated Leukemia | 7 |
| Saint Joseph Hospital - Orange | Advanced Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 7 |
| UC Irvine Health - Chao Family Comprehensive Cancer Center | Gastric Cancer, Hepatocellular Carcinoma, Acute Myeloid Leukemia | 6 |
| UCI Health | Cancer, Crohn's Disease, Fatigue Related to Cancer Treatment | 5 |
| Chao Family Comprehensive Cancer Center | Chronic Lymphocytic Leukemia, Advanced Clear Cell Renal Cell Carcinoma, Endometrial Cancer | 4 |
| Chao Family Comprehensive Cancer Center, University of California Irvine | Allogeneic Stem Cell Transplantation, Breast Cancer, Colorectal Cancer | 4 |
| Children's Hospital of Orange County (CHOC) | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Anti-myostatin | 4 |
| Knowledge Research Center | Colonic Polyps, MASH - Metabolic Dysfunction-Associated Steatohepatitis, Metabolic Dysfunction-Associated Steatotic Liver Disease | 4 |
| Neurocrine Clinical Site | Major Depressive Disorder, Bipolar Disorder, Schizoaffective Disorder | 4 |
| UC Irvine | Autoimmune Encephalitis, Encephalitis, Overactive Bladder (OAB) | 4 |
| UCI Medical Center | Deep Venous Thrombosis, Locally Advanced Solid Tumor, Metastatic Solid Tumor | 4 |
| Center for Inherited Blood Disorders | Hemophilia A, Hemophilia B | 3 |
Active & Upcoming Studies in Orange (2026)
Recruiting trials in Orange grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (221 active studies)
- Testing the Effect of Teclistamab on Recurrent Plasmablastic Lymphoma · Phase 1 · National Cancer Institute (NCI)
- Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma · Phase 2 · University of California, Irvine
Cardiovascular (19 active studies)
- Optimal Ventilation for Cardiac Arrest · Children's Hospital of Philadelphia
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Mental health & behavior (18 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Neurology & pain (18 active studies)
- A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) · Phase 4 · Alpha Cognition, Inc
- Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study · University of California, Irvine
Diabetes & metabolic (14 active studies)
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Pediatric (8 active studies)
- A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors · Phase 1 · Neonc Technologies, Inc.
- Pediatric Down Syndrome Post-Approval Study · Inspire Medical Systems, Inc.
Vaccines (2 active studies)
- Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS) · Children's Hospital of Orange County
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
Eye & vision (2 active studies)
- A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy · Astellas Pharma Global Development, Inc.
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in Orange
- Breast Cancer (10 active studies)
- Ovarian Cancer (9 active studies)
- Acute Myeloid Leukemia (8 active studies)
- Hepatocellular Carcinoma (8 active studies)
- Major Depressive Disorder (8 active studies)
- Endometrial Cancer (7 active studies)
Leading research sponsors in Orange
- University of California, Irvine
- National Cancer Institute (NCI)
- Children's Oncology Group
- Eli Lilly and Company
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Orange?
There are approximately 516 recruiting clinical trials in Orange, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Orange pay participants?
Most recruiting trials in Orange compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Orange?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Orange?
The most common conditions under active study in Orange include Breast Cancer (10), Ovarian Cancer (9), Acute Myeloid Leukemia (8), Hepatocellular Carcinoma (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Orange?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Orange on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Orange?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Orange?
Recruiting research sites in Orange include Children's Hospital of Orange County, UC Irvine Health/Chao Family Comprehensive Cancer Center, University of California Irvine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Orange right now?
The largest active categories in Orange are Cancer & tumors (221), Cardiovascular (19), Mental health & behavior (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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