As of July 2026, 46 paid clinical trials are recruiting for Autoimmune disease in Philadelphia, Pennsylvania. Autoimmune disease research covers a broad spectrum of immune-modulating therapies — JAK inhibitors, biologics, T-cell modulators, and tolerance-inducing agents — across rheumatologic, dermatologic, neurologic, and GI conditions. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Philadelphia has approximately 1,978 recruiting research studies across a wide range of therapeutic areas. Pennsylvania hosts UPenn's Perelman School of Medicine and Children's Hospital of Philadelphia — pioneers in CAR-T cell therapy — alongside UPMC, Thomas Jefferson University, and Penn State Hershey.
Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pennsylvania | Heart Failure, Opioid Use Disorder, Cardiovascular Diseases | 357 |
| Children's Hospital of Philadelphia | High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Pediatric Cancer | 306 |
| Thomas Jefferson University Hospital | Acute Myeloid Leukemia, Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8 | 112 |
| Thomas Jefferson University | Focal Epilepsy, Advanced Melanoma, Cancer | 95 |
| Fox Chase Cancer Center | Breast Cancer, Cancer, Urothelial Carcinoma | 93 |
| Hospital of the University of Pennsylvania | Abdominal Aortic Aneurysm, Breast Cancer, Obstetrical Complications | 87 |
| The Children's Hospital of Philadelphia | Eosinophilic Esophagitis (EoE), Mitochondrial Diseases, Primary Mitochondrial Disease | 42 |
| Temple University | COPD, Amyotrophic Lateral Sclerosis, Emphysema | 39 |
| Temple University Hospital | Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis | 38 |
| University of Pennsylvania/Abramson Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 30 |
| Pennsylvania Hospital | Recurrent Endometrial Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma | 28 |
| Penn Presbyterian Medical Center | Atrial Fibrillation, Heart Failure, ADHF | 27 |
| Abramson Cancer Center of the University of Pennsylvania | Breast Cancer, Advanced Solid Tumor, DLBCL - Diffuse Large B Cell Lymphoma | 26 |
| Saint Christopher's Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 23 |
| Jefferson Torresdale Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 22 |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Parkinson Disease, Stress Disorders, Post-Traumatic, Alcohol Use Disorder | 18 |
| Sidney Kimmel Cancer Center at Thomas Jefferson University | Colorectal Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 15 |
| Drexel University | Autism Spectrum Disorder, Obesity, Anxiety | 13 |
| GSK Investigational Site | Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms | 12 |
| Penn Medicine | Hypertension, ALS, Allogeneic Transplantation | 12 |
| University of Pennsylvania Health System | Behavior, Health, Acute Kidney Injury, Atrial Fibrillation | 12 |
| University of Pennsylvania Hospital | Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma | 12 |
| University of Pennsylvania, Abramson Cancer Center | Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer | 12 |
| Childrens Hospital of Philadelphia | Suicide, Chronic Kidney Disease, Depression | 11 |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer | 11 |
Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Pennsylvania are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Pennsylvania research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Philadelphia from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 1,978 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Philadelphia include Breast Cancer (34), Cancer (24), Heart Failure (20), Ovarian Cancer (20), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Philadelphia are Cancer & tumors (552), Neurology & pain (111), Cardiovascular (104). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.