Oncology Clinical Trials in Philadelphia, PA

As of August 2026, 373 paid clinical trials are recruiting for Oncology in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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Healthy volunteers only

Newly added in Philadelphia

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

for Malnutitrion

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07776704·Recruiting·Listed Aug 20, 2026

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Tai Chi for Reducing Aromatase Inhibitor-Induced Arthralgia

for Hormone Receptor Positive Breast Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT07737951·Recruiting·Listed Jul 30, 2026

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A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

for AML

Sites in Philadelphia +25 more locations

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07702578·Phase 3·Recruiting·Listed Jul 14, 2026

Apply to this trial

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for Diffuse Intrinsic Pontine Glioma

Sites in Philadelphia +5 more locations

Sponsor: BrainChild Bio, Inc

Sex: All·Age: 1 - 26

Code: NCT07680439·Phase 2·Recruiting·Listed Jul 2, 2026

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377 clinical trials for Oncology

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A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

for Solid Tumors

Drug: INCB161734

Sites in Philadelphia, Pittsburgh +68 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07522073·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Philadelphia +29 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Philadelphia +36 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07258511·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

Sites in Philadelphia, Willow Grove +123 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting·Listed Sep 2025

Apply to this trial

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

Sites in Philadelphia, Easton +89 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting·Listed Feb 2024

Apply to this trial

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

for Breast Cancer

Sites in Philadelphia, Wynnewood +170 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06492616·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

Sites in Philadelphia, Hershey +42 more locations

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting·Listed Jan 2022

Apply to this trial

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

Sites in Philadelphia, West Reading +126 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting·Listed Oct 2024

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Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

Sites in Philadelphia, Pittsburgh +89 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06890598·Phase 3·Recruiting·Listed Mar 2025

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

Sites in Philadelphia, Wynnewood +122 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting·Listed Dec 2022

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A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: LY3537982

Sites in Philadelphia, Horsham +86 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06119581·Phase 3·Recruiting·Listed Nov 2023

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A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

for Colorectal Neoplasms

Drug: Amivantamab

Sites in Philadelphia, Pittsburgh +65 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06750094·Phase 3·Recruiting·Listed Dec 2024

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

Sites in Philadelphia, Pittsburgh +78 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting·Listed Oct 2024

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A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for Ovarian Cancer

Sites in Philadelphia, Pittsburgh +25 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07059845·Phase 2·Recruiting·Listed Jul 2025

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

Sites in Philadelphia, Meadowbrook +47 more locations

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting·Listed Feb 2022

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

Sites in Philadelphia, Pittsburgh +40 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting·Listed Apr 2018

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Philadelphia +45 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting·Listed May 2025

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A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

for Advanced Cancer

Sites in Philadelphia +37 more locations

Sponsor: Artios Pharma Ltd

Sex: All·Age: 18+

Code: NCT04657068·Phase 1, Phase 2·Recruiting·Listed Dec 2020

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A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for Endometrial Cancer

Sites in Philadelphia, Bethlehem +44 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06952504·Phase 3·Recruiting·Listed May 2025

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

Sites in Philadelphia, Pittsburgh +76 more locations

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting·Listed Feb 2018

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A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for Breast Neoplasms

Sites in Philadelphia +40 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312176·Phase 3·Recruiting·Listed Mar 2024

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Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

for Large B-cell Lymphoma

Sites in Philadelphia, Pittsburgh +59 more locations

Sponsor: Allogene Therapeutics

Sex: All·Age: 18+

Code: NCT06500273·Phase 2·Recruiting·Listed Jul 2024

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A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

Sites in Philadelphia, Bethlehem +65 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting·Listed Mar 2025

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A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

for Breast Neoplasms

Sites in Philadelphia, Allentown +36 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06926868·Phase 2, Phase 3·Recruiting·Listed Apr 2025

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Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for Non-Small Cell Lung Cancer

Sites in Philadelphia, Pittsburgh +24 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07100080·Phase 2, Phase 3·Recruiting·Listed Aug 2025

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A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for Non-small Cell Lung Cancer

Drug: Intismeran autogene

Sites in Philadelphia +57 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06077760·Phase 3·Recruiting·Listed Oct 2023

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Philadelphia, Hershey +37 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting·Listed Apr 2025

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Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostate Cancer

Sites in Philadelphia, Pittsburgh +19 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT04221542·Phase 1·Recruiting·Listed Jan 2020

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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Philadelphia, Willow Grove +44 more locations

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting·Listed Jan 2025

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FOG-001 in Locally Advanced or Metastatic Solid Tumors

for Cancer

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Parabilis Medicines, Inc.

Sex: All·Age: 18+

Code: NCT05919264·Phase 1, Phase 2·Recruiting·Listed Jun 2023

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Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

for Advanced Solid Tumor

Sites in Philadelphia +23 more locations

Sponsor: Synthekine

Sex: All·Age: 18+

Code: NCT05098132·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

Sites in Philadelphia +48 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting·Listed Apr 2025

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A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for Hormone Receptor Positive HER-2 Negative Breast Cancer

Sites in Philadelphia, Horsham +32 more locations

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06369285·Phase 2·Recruiting·Listed Apr 2024

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

Sites in Philadelphia +31 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting·Listed Aug 2024

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Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

Sites in Philadelphia, Allentown +30 more locations

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

Sites in Philadelphia, Lancaster +38 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting·Listed Aug 2024

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

Drug: JANX007

Sites in Philadelphia, Hershey +31 more locations

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting·Listed Aug 2022

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A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for Multiple Myeloma

Sites in Philadelphia, Pittsburgh +26 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05201781·Phase 4·Recruiting·Listed Jan 2022

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

Sites in Philadelphia +28 more locations

Sponsor: Fore Biotherapeutics

Sex: All·Age: 8+

Code: NCT05503797·Phase 2·Recruiting·Listed Aug 2022

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Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

Sites in Philadelphia +31 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

Top Research Study Locations in Philadelphia

Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

Site	Specializes in	Active trials
University of Pennsylvania	Heart Failure, Opioid Use Disorder, Colorectal Cancer	358
Children's Hospital of Philadelphia	Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Pediatric Cancer	302
Thomas Jefferson University Hospital	Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8	110
Thomas Jefferson University	Focal Epilepsy, Advanced Melanoma, Cancer	97
Fox Chase Cancer Center	Breast Cancer, Cancer, Urothelial Carcinoma	95
Hospital of the University of Pennsylvania	Abdominal Aortic Aneurysm, Breast Cancer, Aortic Dissection	87
Temple University	Amyotrophic Lateral Sclerosis, COPD, Emphysema	41
The Children's Hospital of Philadelphia	Mitochondrial Diseases, Primary Mitochondrial Disease, 4H Syndrome	40
Temple University Hospital	Interstitial Lung Disease, Progressive Pulmonary Fibrosis, COPD	35
University of Pennsylvania/Abramson Cancer Center	Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy	31
Pennsylvania Hospital	Stroke, Acute, Activity Restriction, Advanced Cancer	28
Penn Presbyterian Medical Center	Atrial Fibrillation, Heart Failure, ADHF	26
Abramson Cancer Center of the University of Pennsylvania	Breast Cancer, Advanced Solid Tumor, DLBCL - Diffuse Large B Cell Lymphoma	25
Jefferson Torresdale Hospital	Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8	23
Saint Christopher's Hospital for Children	Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia	22
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA	Parkinson Disease, Stress Disorders, Post-Traumatic, Alcohol Use Disorder	18
Sidney Kimmel Cancer Center at Thomas Jefferson University	Breast Cancer, Colorectal Cancer, Hormone Receptor Positive Breast Carcinoma	16
Drexel University	Autism Spectrum Disorder, Obesity, Anxiety	13
Penn Medicine	Hypertension, ALS, Allogeneic Transplantation	13
University of Pennsylvania Hospital	Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma	13
GSK Investigational Site	Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms	12
Childrens Hospital of Philadelphia	Suicide, Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR)	12
University of Pennsylvania, Abramson Cancer Center	Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer	12
Abramson Cancer Center at University of Pennsylvania	Cardiotoxicity, Renal Cell Carcinoma, AML, Adult	10
Thomas Jefferson University, Sidney Kimmel Cancer Center	Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer	10

Active & Upcoming Studies in Philadelphia (2026)

Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Common conditions studied in Philadelphia

Breast Cancer (36 active studies)
Cancer (25 active studies)
Heart Failure (21 active studies)
Ovarian Cancer (21 active studies)
Prostate Cancer (21 active studies)
Advanced Solid Tumor (18 active studies)

Leading research sponsors in Philadelphia

University of Pennsylvania
Abramson Cancer Center at Penn Medicine
Children's Hospital of Philadelphia
Thomas Jefferson University
National Cancer Institute (NCI)

Frequently asked questions

How many paid clinical trials are currently recruiting in Philadelphia?

There are approximately 1,986 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Philadelphia pay participants?

Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Philadelphia?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Philadelphia?

The most common conditions under active study in Philadelphia include Breast Cancer (36), Cancer (25), Heart Failure (21), Ovarian Cancer (21), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Philadelphia?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Philadelphia?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Philadelphia?

Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Philadelphia right now?

The largest active categories in Philadelphia are Cancer & tumors (556), Neurology & pain (111), Cardiovascular (110). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Other cities in Pennsylvania

Pittsburgh, PA(1,242)Hershey, PA(267)Allentown, PA(127)Danville, PA(125)Bethlehem, PA(99)York, PA(94)Erie, PA(86)Wilkes-Barre, PA(78)Lancaster, PA(70)Monroeville, PA(65)Harrisburg, PA(59)Wynnewood, PA(52)Lewisburg, PA(50)Hazleton, PA(46)Willow Grove, PA(45)Mechanicsburg, PA(40)East Stroudsburg, PA(39)West Reading, PA(39)Greensburg, PA(35)Media, PA(35)Scranton, PA(34)Sayre, PA(33)Duncansville, PA(32)Uniontown, PA(32)Chambersburg, PA(31)Dickson City, PA(31)Chadds Ford, PA(29)University Park, PA(29)Lebanon, PA(28)DuBois, PA(27)Beaver, PA(24)Camp Hill, PA(24)Ephrata, PA(24)Gettysburg, PA(24)Pottsville, PA(24)West Chester, PA(24)Wyomissing, PA(24)Bala-Cynwyd, PA(23)Farrell, PA(23)Paoli, PA(23)Wexford, PA(23)Washington, PA(22)Easton, PA(21)Altoona, PA(20)Indiana, PA(20)Johnstown, PA(20)New Castle, PA(20)Plymouth Meeting, PA(20)Seneca, PA(20)Butler, PA(19)Jefferson Hills, PA(19)State College, PA(19)Abington, PA(18)Bryn Mawr, PA(18)Cranberry Township, PA(16)Natrona Heights, PA(16)Smithfield, PA(16)Carlisle, PA(15)Williamsport, PA(15)Horsham, PA(13)

Related healthcare resources in Pennsylvania

Latest Philadelphia, PA clinical trials research report

Trials by condition in Philadelphia

Breast Cancer· 36 Heart Failure· 21 Ovarian Cancer· 21 Prostate Cancer· 21 Colorectal Cancer· 18 Endometrial Cancer· 18

Conditions in Oncology (Philadelphia, PA)

Solid tumor· 57 Breast cancer· 43 Non-small cell lung cancer (NSCLC)· 38 Cancer (any)· 38 Colorectal cancer· 26 Prostate cancer· 24 Ovarian cancer· 24 Acute myeloid leukemia (AML)· 24 Pancreatic cancer· 19 Endometrial cancer· 18 Non-Hodgkin lymphoma· 18 Head and neck cancer· 18 Gastric cancer· 14 Bladder cancer· 13 Diffuse large B-cell lymphoma (DLBCL)· 13 Glioma· 12 Multiple myeloma· 12 Hematologic malignancy· 12 Metastatic prostate cancer· 10 Kidney cancer· 10 Myelodysplastic syndromes (MDS)· 10 Lung cancer· 9 Esophageal cancer· 9 Liver cancer· 9 Leukemia (other)· 9 Melanoma· 9 Fallopian tube cancer· 8 Neuroblastoma· 8 Pediatric cancer· 8 Chronic lymphocytic leukemia (CLL)· 7 Neuroendocrine tumors· 7 Metastatic breast cancer· 6 Biliary tract cancer· 6 Cervical cancer· 6 Glioblastoma· 6 Hodgkin lymphoma· 6 Ewing sarcoma· 6 Triple-negative breast cancer· 5 Gastroesophageal junction cancer· 5 Osteosarcoma· 5 Acute lymphoblastic leukemia· 4 Myelofibrosis· 4 Small lymphocytic lymphoma· 4 HER2-positive breast cancer· 3 HER2-negative breast cancer· 3 Small cell lung cancer· 3 Myeloproliferative neoplasm· 3 Follicular lymphoma· 3 Burkitt lymphoma· 3 Thyroid cancer· 3 Rhabdomyosarcoma· 3 Gastrointestinal cancer· 2 Uterine cancer· 2 Brain cancer· 2 Mantle cell lymphoma· 2 Marginal zone lymphoma· 2 Soft tissue sarcoma· 2 Metastatic colorectal cancer· 1 Chronic myelomonocytic leukemia· 1 Skin cancer· 1 Sarcoma· 1 Mesothelioma· 1

Oncology Clinical Trials in Philadelphia, PA

Newly added in Philadelphia

377 clinical trials for Oncology

Top Research Study Locations in Philadelphia

Active & Upcoming Studies in Philadelphia (2026)

Cancer & tumors (556 active studies)

Neurology & pain (111 active studies)

Cardiovascular (110 active studies)

Diabetes & metabolic (65 active studies)

Mental health & behavior (49 active studies)

Pediatric (47 active studies)

HIV / STI (27 active studies)

Eye & vision (23 active studies)

Vaccines (7 active studies)

Common conditions studied in Philadelphia

Leading research sponsors in Philadelphia

Frequently asked questions

How many paid clinical trials are currently recruiting in Philadelphia?

Do clinical trials in Philadelphia pay participants?

Who can participate in a clinical trial in Philadelphia?

What conditions are most commonly studied in Philadelphia?

Are there clinical trials for healthy volunteers in Philadelphia?

How do I enroll in a clinical trial in Philadelphia?

Where can I take part in paid clinical trials in Philadelphia?

What kinds of studies are recruiting in Philadelphia right now?

Browse more clinical trials

Other cities in Pennsylvania

Related healthcare resources in Pennsylvania

Trials by condition in Philadelphia

Conditions in Oncology (Philadelphia, PA)