HIV Clinical Trials in San Francisco, CA
As of August 2026, 24 paid clinical trials are recruiting for HIV in San Francisco, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in San Francisco
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
25 clinical trials for HIV
·Clear filters·A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1
Imaging Immune Activation in HIV by PET-MR
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women
Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity
The Use of Leukapheresis to Support HIV Pathogenesis Studies
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
Collection of Blood for Multiple Collaborative Studies
CAR-T Cells for HIV Infection
Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation
Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
Feasibility of HPV Testing With Mail-delivered Sample Collection Kits
Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
SCOPE: Observational Study of the Consequences of the Protease Inhibitor Era
PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)
Observational PIC Destination Cohort
Text Education About Cardiovascular Health and HIV (TEACH-HIV)
PrEPsmart 2-1-1 Pilot
Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention
A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies
Small Trial of Alendronate Impact on the Reservoir of HIV
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
Top Research Study Locations in San Francisco
Researchers run research studies in San Francisco, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California, San Francisco | Prostate Cancer, Glioblastoma, Epilepsy | 320 |
| University of California San Francisco | Multiple Myeloma, Prostate Cancer, Breast Cancer | 164 |
| Power Life Sciences | Acne, Anorexia, Anorexia Nervosa | 51 |
| UCSF | Colorectal Cancer, Tricuspid Valve Disease, ADHD | 33 |
| Kaiser Permanente-San Francisco | Stage IV Lung Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma | 32 |
| UCSF Medical Center-Mission Bay | B Acute Lymphoblastic Leukemia, Neuroblastoma, Acute Myeloid Leukemia | 32 |
| Zuckerberg San Francisco General Hospital | Cardiovascular Diseases, HIV, Healthy | 26 |
| UCSF Medical Center | Stroke, Aneurysm, Aneurysm, Intracranial | 23 |
| California Pacific Medical Center-Pacific Campus | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 22 |
| UCSF Helen Diller Family Comprehensive Cancer Center | Advanced Breast Cancer, Breast Cancer, Solid Tumor, Adult | 21 |
| University of California | Aortic Valve Regurgitation, Aortic Valve Stenosis, Articular Cartilage | 19 |
| San Francisco VA Medical Center, San Francisco, CA | PTSD, Sleep Initiation and Maintenance Disorders, Aging | 16 |
| University of California, San Francisco (UCSF) | Colorectal Cancer, Non-small Cell Lung Cancer, Acquired Resistance to KRAS G12C Inhibitor | 15 |
| UCSF Benioff Children's Hospital | 4H Syndrome, ADLD, AGS | 14 |
| California Pacific Medical Center | Amyotrophic Lateral Sclerosis, Amyotrophic Lateral Sclerosis (ALS), Melanoma | 12 |
| San Francisco General Hospital | HIV, HIV Infections, Intracerebral Hemorrhage | 12 |
| San Francisco Research Institute | Women Health, Anxiety, Cognitive Decline | 10 |
| Alethios, Inc. | Abdominal Discomfort, Digestive Health, Digestive Well Being | 9 |
| San Francisco VA Medical Center | Atopic Dermatitis, Eczema, Atopic Dermatitis (Eczema) | 9 |
| UCSF Medical Center-Parnassus | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 8 |
| University of California - San Francisco | Diabetes, Diabetic Foot, Diabetic Foot Ulcer | 8 |
| University of California San Francisco (UCSF) | Melanoma, Advanced Solid Tumors, Angiosarcoma | 8 |
| University of California at San Francisco | Advanced Tumors, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| University of San Francisco | Cone Rod Dystrophy, Juvenile Macular Degeneration, Stargardt Disease | 7 |
| UCSF Medical Center at Mission Bay | Breast Cancer, Atrial Fibrillation (AF), Atrial Fibrillation (Paroxysmal) | 6 |
Active & Upcoming Studies in San Francisco (2026)
Recruiting trials in San Francisco grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (397 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease · University of California, San Francisco
Neurology & pain (83 active studies)
- Alzheimer's Tau Platform: Regimen A - AADvac1 · Phase 2 · Paul S. Aisen
- An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service · Phase 3 · University of California, San Francisco
Cardiovascular (82 active studies)
- Naloxone for Opioid Associated Out of Hospital Cardiac Arrest · Phase 2 · University of California, San Francisco
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Mental health & behavior (49 active studies)
- LIFU Effects & Outcomes: Mechanisms Evaluating Striatal Systems Imaging (LEO MESSI) · University of California, San Francisco
- Facilitating Transition to Recommended PTSD Treatment · VA Office of Research and Development
HIV / STI (48 active studies)
- Psilocybin Therapy for Methamphetamine Use Disorder and HIV · Phase 2 · Nicky Mehtani, MD, MPH
- Short-term Effects of Methamphetamine on Residual Latent HIV Disease Study · Phase 4 · University of California, San Francisco
Diabetes & metabolic (37 active studies)
- PRISE (Personalized Response and Immunologic Surveillance of Endogenous C-Peptide Preservation in New, Recent, and Established Onset Type 1 Diabetes Treated With Human Anti-Thymocyte Globulin [h-ATG]) Study · Phase 3 · University of Florida
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
Pediatric (22 active studies)
- Prenatal Transplantation for Fetuses With Fanconi Anemia · Phase 1, Phase 2 · Agnieszka Czechowicz
- Music Therapy for Oral Mucositis Pain in Pediatric Patients · University of California, San Francisco
Eye & vision (19 active studies)
- Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center · University of California, San Francisco
- Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes · University of California, San Francisco
Vaccines (13 active studies)
- Validation of Biomarkers for Long COVID in the LIINC Viral Immunopathogenesis and Persistence Repeat Donor Cohort (VIPER) · University of California, San Francisco
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
Common conditions studied in San Francisco
- Breast Cancer (28 active studies)
- Prostate Cancer (27 active studies)
- Heart Failure (18 active studies)
- HIV (16 active studies)
- Cancer (13 active studies)
- Solid Tumor (13 active studies)
Leading research sponsors in San Francisco
- University of California, San Francisco
- Power Life Sciences Inc.
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in San Francisco?
There are approximately 1,349 recruiting clinical trials in San Francisco, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Francisco pay participants?
Most recruiting trials in San Francisco compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Francisco?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Francisco?
The most common conditions under active study in San Francisco include Breast Cancer (28), Prostate Cancer (27), Heart Failure (18), HIV (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Francisco?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Francisco on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Francisco?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Francisco?
Recruiting research sites in San Francisco include University of California, San Francisco, University of California San Francisco, Power Life Sciences, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Francisco right now?
The largest active categories in San Francisco are Cancer & tumors (397), Neurology & pain (83), Cardiovascular (82). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.