Paid Clinical Trials in San Mateo, CA
As of August 2026, 31 paid clinical trials are recruiting in San Mateo, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Mateo offers studies at sites including Mills Health Center for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Mateo
Trials by drug in San Mateo
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29 clinical trials
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
The PREDICT Registry:
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Top Research Study Locations in San Mateo
Researchers run research studies in San Mateo, CA at 14 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mills Health Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma | 21 |
| Carbon Health - San Mateo - Hillsdale Mall | Clostridioides Difficile Associated Disease | 1 |
| Dorothy Schneider Cancer Center | Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases | 1 |
| Evidation Health | Substance Use Disorder (SUD) | 1 |
| Hoyman Hong | Lumbar Spinal Stenosis | 1 |
| Mills Health Ctr | Lumbar Spinal Stenosis | 1 |
| Mills-Peninsula Medical Center - San Mateo Campus | Diabetes, Diabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 2 | 1 |
| Mills-Peninsula Medical Center: Diabetes Research Institute | Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus | 1 |
| Palo Alto Medical Foundation - San Mateo Care Center | Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases | 1 |
| Palo Alto Medical Foundation Research Center | Breast Cancer | 1 |
| Research at Mills-Peninsula Medical Center - Sutter Health | Hypothyroidism | 1 |
| San Mateo Surgery Center | Lumbar Spinal Stenosis | 1 |
| Sutter Health | DCIS, Ductal Breast Carcinoma In Situ, Stage 0 Breast Cancer | 1 |
| UCSF Cancer Center San Mateo | Breast Cancer | 1 |
Active & Upcoming Studies in San Mateo (2026)
Recruiting trials in San Mateo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (23 active studies)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
Diabetes & metabolic (3 active studies)
- Argus 2.0 Adoption Study · KOS Inc.
- GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes · Medtronic MiniMed, Inc.
Mental health & behavior (1 active study)
Common conditions studied in San Mateo
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
- Recurrent Lung Non-Small Cell Carcinoma (3 active studies)
- Stage IV Lung Cancer AJCC v8 (3 active studies)
- Anatomic Stage IIIB Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in San Mateo
- SWOG Cancer Research Network
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- National Cancer Institute (NCI)
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in San Mateo?
There are approximately 31 recruiting clinical trials in San Mateo, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Mateo pay participants?
Most recruiting trials in San Mateo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Mateo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Mateo?
The most common conditions under active study in San Mateo include Anatomic Stage II Breast Cancer AJCC v8 (4), Anatomic Stage IIIA Breast Cancer AJCC v8 (3), Breast Cancer (3), Recurrent Lung Non-Small Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Mateo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Mateo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Mateo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Mateo?
Recruiting research sites in San Mateo include Mills Health Center, Carbon Health - San Mateo - Hillsdale Mall, Dorothy Schneider Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Mateo right now?
The largest active categories in San Mateo are Cancer & tumors (23), Diabetes & metabolic (3), Mental health & behavior (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.