Paid Clinical Trials in Santa Ana, CA
As of July 2026, 49 paid clinical trials are recruiting in Santa Ana, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Santa Ana offers studies at sites including Syrentis Clinical Research for conditions such as Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2, Alzheimer Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Santa Ana
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Researchers run research studies in Santa Ana, CA at 24 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Syrentis Clinical Research | Alzheimer Disease, Alzheimers Disease, AD | 6 |
| Southern California Clinical Research | Obesity, Overweight, Alopecia Areata | 4 |
| Orange County Retina Medical Group | Age-related Macular Degeneration (AMD), Geographic Atrophy (GA), Geographic Atrophy Secondary to Age-related Macular Degeneration | 4 |
| Santa Ana, California | Idiopathic Hypersomnia, Narcolepsy Type 1, Narcolepsy Type 2 | 3 |
| Wolverine Clinical Trials | Hidradenitis Suppurativa, Osteoarthritis, Overweight or Obesity | 3 |
| Oruka Therapeutics Investigative Site | Plaque Psoriasis | 2 |
| SDS Clinical Trials, Inc. | Narcolepsy Type 1, OSA | 2 |
| Southern California Dermatology, Inc. | Alopecia, Areata Alopecia, Hair Diseases | 2 |
| Takeda | Idiopathic Hypersomnia, Narcolepsy Type 2 | 2 |
| Akerman Med | Bacterial Vaginosis, Fungal Vaginal Infections | 1 |
| Altamed Dental Clinic | Behavior Change, Dental Anxiety in Children | 1 |
| Artiva Investigational Site Santa Ana | IIM, Idiopathic Inflammatory Myopathies (IIMs), Myositis | 1 |
| Clemente Clinical Research | Diabetic Foot Ulcer, Wound Heal | 1 |
| Helping Hands Medical Associates INC | Cardiovascular Disease and Lipoprotein(a) | 1 |
| Local Institution - 007-898-C | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Novartis Investigative Site | Atopic Dermatitis | 1 |
| Orange County Retina Med Group | Neovascular Age-related Macular Degeneration | 1 |
| Paje Optometric | Juvenile Myopia, Myopia, Myopia Progression | 1 |
| Paragon RX Clinical | Osteoarthritis, Knee | 1 |
| Paragon Rx Clinical, Inc. - Santa Ana | Chronic Idiopathic Constipation (CIC) | 1 |
| SDS Clinical Trials, Inc-California-Santa Ana | Narcolepsy | 1 |
| Southern California Dermatology | Dermatitis Atopic | 1 |
| UCI Health Family Health Center - Santa Ana | Early Detection of Cancer, Lung Cancer Screening, Lung Neoplasms | 1 |
| UCI Medical Center- Central Distribution Warehouse - Dyer | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Santa Ana (2026)
Recruiting trials in Santa Ana grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Eye & vision (6 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO · Phase 2 · EyeBiotech Ltd.
Diabetes & metabolic (5 active studies)
- Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH) · Phase 3 · Amgen
- A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin · Phase 3 · Eli Lilly and Company
Neurology & pain (3 active studies)
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
- Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) · Cognito Therapeutics, Inc.
Mental health & behavior (2 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Tactile Pre-Visit Imagery · University of Southern California
Cancer & tumors (2 active studies)
- Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+) · University of California, Irvine
- Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7 · Phase 2, Phase 3 · Mirati Therapeutics Inc.
Pediatric (1 active study)
- Tactile Pre-Visit Imagery · University of Southern California
Common conditions studied in Santa Ana
- Idiopathic Hypersomnia (3 active studies)
- Narcolepsy Type 1 (3 active studies)
- Narcolepsy Type 2 (3 active studies)
- Alzheimer Disease (2 active studies)
- Alzheimers Disease (2 active studies)
- Binge-Eating Disorder (2 active studies)
Leading research sponsors in Santa Ana
- Eli Lilly and Company
- Axsome Therapeutics, Inc.
- Takeda
- AbbVie
- Centessa Pharmaceuticals (UK) Limited
Frequently asked questions
How many paid clinical trials are currently recruiting in Santa Ana?
There are approximately 49 recruiting clinical trials in Santa Ana, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Santa Ana pay participants?
Most recruiting trials in Santa Ana compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Santa Ana?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Santa Ana?
The most common conditions under active study in Santa Ana include Idiopathic Hypersomnia (3), Narcolepsy Type 1 (3), Narcolepsy Type 2 (3), Alzheimer Disease (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Santa Ana?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Santa Ana on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Santa Ana?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Santa Ana?
Recruiting research sites in Santa Ana include Syrentis Clinical Research, Southern California Clinical Research, Orange County Retina Medical Group, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Santa Ana right now?
The largest active categories in Santa Ana are Eye & vision (6), Diabetes & metabolic (5), Neurology & pain (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.