Paid Clinical Trials in Smithfield, PA
As of July 2026, 14 paid clinical trials are recruiting in Smithfield, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Smithfield offers studies at sites including Frontier Clinical Research, LLC for conditions such as Migraine, Diabetes Mellitus, Type 2, Acute Migraine, Asthma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Smithfield
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·Clear filters·Top Research Study Locations in Smithfield
Researchers run research studies in Smithfield, PA at 3 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Frontier Clinical Research, LLC | Acute Migraine, Diabetes Mellitus, Type 2, Irritable Bowel Syndrome With Constipation (IBS-C) | 5 |
| Frontier Clinical Research - Smithfield | Migraine, Chronic Migraine | 3 |
| Frontier Clinical Research | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension | 2 |
Active & Upcoming Studies in Smithfield (2026)
Recruiting trials in Smithfield grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Neurology & pain (5 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Vaccines (2 active studies)
- A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine · Phase 3 · Pfizer
- A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts · Phase 3 · Hoffmann-La Roche
Diabetes & metabolic (2 active studies)
- A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes · Phase 3 · Eli Lilly and Company
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
Cardiovascular (2 active studies)
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
- Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin · Phase 3 · AstraZeneca
Common conditions studied in Smithfield
- Migraine (3 active studies)
- Diabetes Mellitus, Type 2 (2 active studies)
- Acute Migraine (1 active study)
- Asthma (1 active study)
- Cardiovascular Disease (1 active study)
- Cardiovascular Diseases (1 active study)
Leading research sponsors in Smithfield
- AstraZeneca
- AbbVie
- Kallyope Inc.
- Ardelyx
- Boehringer Ingelheim
Frequently asked questions
How many paid clinical trials are currently recruiting in Smithfield?
There are approximately 14 recruiting clinical trials in Smithfield, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Smithfield pay participants?
Most recruiting trials in Smithfield compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Smithfield?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Smithfield?
The most common conditions under active study in Smithfield include Migraine (3), Diabetes Mellitus, Type 2 (2), Acute Migraine (1), Asthma (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Smithfield?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Smithfield on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Smithfield?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Smithfield?
Recruiting research sites in Smithfield include Frontier Clinical Research, LLC, Frontier Clinical Research - Smithfield, Frontier Clinical Research, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Smithfield right now?
The largest active categories in Smithfield are Neurology & pain (5), Vaccines (2), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.