Knee osteoarthritis Clinical Trials
Recruiting knee osteoarthritis studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.
Clinical trials study new ways to prevent, detect, or treat knee osteoarthritis. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting knee osteoarthritis studies with sites across the US; use the location tools to find ones near you.
What to expect
- Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
- Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
- No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.
Recruiting knee osteoarthritis trials
Zynrelef Versus Adductor Canal Block
Heart Rate Variability Guided Physical Activity and Exercise Prescription in Individuals With Knee Osteoarthritis
Efficacy of Autologous Adipose Derived Stromal Vascular Fraction for Musculoskeletal Conditions
A Study Evaluating the Safety, Tolerability, and Activity of ICM-203 in Subjects With Knee Osteoarthritis.
Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis
NANOVAE to Treat Knee Osteoarthritis (KOA)
Blood Cell Ratios as Predictors of Response to Platelet-Rich Plasma in Knee Osteoarthritis
Intra Articular Injection of Peripheral Blood Mononuclear Cells for Knee Osteoarthritis
Effect of Inspiratory Muscle Training on Knee Osteoarthritis Pain
Effects of Music During Walking on Pain and Muscle Activation in People With Chronic Pain Due to Knee Osteoarthritis
Effect of Tergase Injection on Reducing Edema After Bilateral Total Knee Arthroplasty
Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Robotic-Assisted Versus Conventional Total Knee Arthroplasty With Virtual Home-Based Rehabilitation
Shock Wave Treatment in Patients With Knee Osteoarthritis
Standard Versus Novel RFA for Chronic Knee Pain in Osteoarthritis
Genicular Artery Embolization for Knee Osteoarthritis
The Effect of Lipedema on Knee Osteoarthritis
Self-managed vs Supervised Exercise for Knee OA
Boosting Exercise Adherence in Knee Osteoarthritis
MECHANICAL TRACTION APPLIED BEFORE VERSUS AFTER THERAPEUTIC EXERCISES IN PRIMARY KNEE OSTEOARTHRITIS
Effects of Sahrmann's Approach Versus Conventional Treatment Oin Patients With Knee Osteoarthritis
Health Aid for Knee Osteoarthritis
ACB and iPACK Blocks With Intravenous Dexamethasone and Perineural Dexmedetomidine in Total Knee Arthroplasty
Artificial Intelligence-Assisted Advanced Analysis of Knee Imaging and Outcome Prediction
IMAGES: Identifying Metabolic Imaging Association With Genicular Artery Embolization Success
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
Clinical Trial to Evaluate the Efficacy and Safety of Conjuran® After First and Second Cycle (Repeat) Administration in Patients With Knee Osteoarthritis
Effect of Alexithymia on Response to Physical Therapy in Patients With Knee Osteoarthritis
Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis
Circulatory Exercise After Total Knee Replacement
Effect of TECAR Therapy on Pain, Balance, and Quality of Life in Elderly Men With Knee Osteoarthritis
Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
Comparative Study on the Medium- and Long-term Benefits of Prosthesis Selection in Total Knee Arthroplasty
Effects of Two Bar Knee Off-Load Brace With Non Weight Bearing Strength Training Among Knee Osteoarthritis Patients
Effects of the Egoscue Exercises With and Without Mwm Among Patients With Knee Osteoarthritis
Effects of a Machine Learning-based Lower Limb Exercise Training System for Knee Pain
Nerve to Vastus Medialis Branches in Chronic Knee Pain
Phonophoresis With Bee Venom: Evaluating Its Efficacy in Managing Pain and Enhancing Mobility in Knee Osteoarthritis Patients
Effect of AI-Assisted Anatomical Visualization on Anxiety and Kinesiophobia in Knee Arthroplasty Patients
The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.
Sonographic Thigh Adjustment Ratio and Subcutaneous Fat Thickness as Predictors of Genicular Nerve Block Response in Knee Osteoarthritis
Efficacy of Artificial Intelligence-Assisted Therapeutic Exercise in Patients With Knee Osteoarthritis
Comparison of Aquatic and Land-Based Mulligan Mobilization With Movement in Knee Osteoarthritis
Integrated Trunk Stabilization With Osteoarthritis Rehabilitation in Knee-Spine Syndrome
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing After Total Knee Arthroplasty (TKA)
Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty
Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0
Serum COMP and MMP-3 in Knee Osteoarthritis
Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms
ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Phase Ib Trial of Injectable RAB001 for Knee Osteoarthritis
Mobile Technology to Measure Knee Health in Osteoarthritis
Serum Fetuin-A and COMP Levels in Knee Osteoarthritis
Oral vs Intravenous Dexamethasone in Total Knee Arthroplasty
Knee Pain Ejiao Paste for Knee Osteoarthritis
Knee osteoarthritis clinical trials — common questions
Are knee osteoarthritis clinical trials free to join?
Yes. Participating in a knee osteoarthritis clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.
Who can join a knee osteoarthritis clinical trial?
Each knee osteoarthritis study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.
How do I find a knee osteoarthritis trial near me?
Use the location controls above. We'll show recruiting knee osteoarthritis trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.
How many knee osteoarthritis trials are recruiting right now?
We're currently tracking roughly 92 recruiting knee osteoarthritis trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.
Looking for a specific location? Browse trials by city and state.