Sarcopenia Clinical Trials

Recruiting sarcopenia studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat sarcopenia. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting sarcopenia studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting sarcopenia trials

Within

Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors

for Critical Illness

1 site in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 60 - 99

Code: NCT05326633·EARLY_Phase 1

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

for Obesity and Obesity-related Medical Conditions

1 site in Columbia

Sponsor: Bettina Mittendorfer

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07083557

Apply to this trial

The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM)

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: Universiti Teknologi Mara

Sex: All·Age: 18 - 65

Code: NCT07664501

HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide

for Type 2 Diabetes Mellitus (T2DM)

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 65 - 85

Code: NCT07760948·Phase 2

Effectiveness of Combined GLP-1/GIP Dual Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals

for Obesity

Sponsor: Acibadem University

Sex: All·Age: 18 - 65

Code: NCT07609160

Muscle Aging Phenotypes in Childhood Cancer Survivors

for Muscle Weakness

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07531498

Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.

for Frailty/Sarcopenia

Sponsor: Universidad de Granada

Sex: All·Age: 65+

Code: NCT07732478

Optimizing Adaptive Intensive Behavioral Therapy for Obesity During the Transition to Older Adulthood

for Obesity & Overweight

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50 - 75

Code: NCT07446907

Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes

for Obesity

Sponsor: University Hospital, Toulouse

Sex: All·Age: 45 - 70·Accepts healthy volunteers

Code: NCT07075133

Multicomponent Training and Muscle Quality in Older Women

for Sarcopenia

Sponsor: University of Salamanca

Sex: Female·Age: 60+·Accepts healthy volunteers

Code: NCT07359495

The SHAPE Project (Hospital System for Physical Activity and Active Participation) After Hospitalized Decompensation of Respiratory Chronic Diseases

for Frailty

Sponsor: Hospital Universitari de Bellvitge

Sex: All·Age: 18+

Code: NCT07663955

Exercise Intervention for Breast Cancer Patients With Sarcopenia

for Sarcopenia

Sponsor: Capital Medical University

Sex: All·Age: 18+

Code: NCT07732101

HB05P on Muscle Health

for Sarcopenia

Sponsor: Pusan National University Yangsan Hospital

Sex: All·Age: 50 - 79·Accepts healthy volunteers

Code: NCT07749118

Apply to this trial

Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia

for Sarcopenia

Sponsor: Chang Gung Memorial Hospital

Sex: All·Age: 50+

Code: NCT07757984

STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With Aging

for Sarcopenia

Sponsor: University of Leicester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07726498

GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery

for Hip Fracture

Sponsor: Fatih Sultan Mehmet Training and Research Hospital

Sex: All·Age: 65+

Code: NCT07751692

Sarcopenia in Acute Ischemic Stroke

for Sarcopenia

Sponsor: University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)

Sex: All·Age: 50+

Code: NCT07764172

Apply to this trial

GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD

for COPD

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 40 - 80

Code: NCT07747805·Phase 2

Sarcopenia in Chronic Kidney Disease (CKD) Patients

for Chronic Kidney Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 45 - 75

Code: NCT07437053·EARLY_Phase 1

Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings

for Cirrhosis of the Liver

Sponsor: Assiut University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07667608

Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship

for Sarcopenia

Sponsor: Ankara City Hospital Bilkent

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07688941

The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.

for Secondary Osteoporosis

1 site in West Orange

Sponsor: Bronx VA Medical Center

Sex: All·Age: 21 - 60

Code: NCT07325149

Sarcopenia Screening in Advanced Coxarthrosis: The SARCO-COX Study

for Sarcopenia

Sponsor: Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

Sex: All·Age: 65+

Code: NCT07734129

Nutritional Status in Hospitalized Patients Over 65 Years of Age With Mental Disorders

for Malnutrition

Sponsor: University Psychiatric Clinic Ljubljana

Sex: All·Age: 65+

Code: NCT07710456

Effectiveness of a ReMIND Diet Intervention on Sarcopenia, Cognitive Frailty and Nutritional Status in Older Adults

for Sarcopenia

Sponsor: Universiti Putra Malaysia

Sex: All·Age: 60 - 84·Accepts healthy volunteers

Code: NCT07325760

Multidimensional Determinants of Functional Health In Women Aged 45-60

for Healthy

Sponsor: Kartal City Hospital

Sex: Female·Age: 45 - 60·Accepts healthy volunteers

Code: NCT07667699

Clinical Study of TJ0113 Capsule in the Treatment of Patients With Sarcopenia

for Sarcopenia

Sponsor: Hangzhou PhecdaMed Co., Ltd.

Sex: All·Age: 60+

Code: NCT07620938·Phase 2

Apply to this trial

Clinical Trial to Evaluate the Efficacy of Neuromuscular Electrical Stimulation Therapy in Patients With Sarcopenia

for Sarcopenia

Sponsor: Exosystems

Sex: All·Age: 50 - 85

Code: NCT07668258

Mental Effort During Low Load Resistance Training in Older Adults

for Seniors

1 site in Kennesaw

Sponsor: Kennesaw State University

Sex: All·Age: 65 - 85·Accepts healthy volunteers

Code: NCT07687316

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Morphological and Functional Biomarkers of Skeletal Muscle Adaptations in Sarcopenia

for Sarcopenia

Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07692308

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Effects of Rehabilitative Exergame Training on Foot Muscle Activity, Balance, and Mobility in Older Adults

for Aging

Sponsor: Tarsus University

Sex: All·Age: 65 - 80

Code: NCT07357662

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CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease

for Sarcopenia

Sponsor: Nemocnice AGEL Trinec-Podlesi a.s.

Sex: All·Age: 18+

Code: NCT07433309

Acute Sarcopenia in Hospitalized Older Adults

for Sarcopenia

Sponsor: IRCCS San Raffaele

Sex: All·Age: 65+

Code: NCT07454759

Magnesium Supplementation as a Nutritional Intervention in Sarcopenia

for Sarcopenia

Sponsor: Escola Superior de Saúde - Universidade do Algarve

Sex: All·Age: 70+·Accepts healthy volunteers

Code: NCT07567963

Serum Insulin-like Growth Factor-1 to Albumin Ratio as a Biomarker for Sarcopenia Severity in End-Stage Renal Disease Patients on Hemodialysis

for Sarcopenia

Sponsor: Sohag University

Sex: All·Age: 18+

Code: NCT07586956

Osteoporosis and Sarcopenia Prevention in Middle-Aged Population

for Osteoporosis

Sponsor: The University of Hong Kong

Sex: All·Age: 40 - 60·Accepts healthy volunteers

Code: NCT07611097

Silkworm Pupa Powder Improves Alzheimer's Disease

for Alzheimer Disease

Sponsor: Zhejiang Provincial Tongde Hospital

Sex: All·Age: 50 - 90

Code: NCT07638449

Association Between Sarcopenia, Fatigue and Orthostatic Intolerance in Geriatric Patients: A Case Control Study

for Sarcopenia

Sponsor: Ain Shams University

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07564830

Prevalence of Sarcopenia and Its Associated Factors in Patients With Knee Osteoarthritis in a Tertiary Care Hospital in Upper Egypt

for Osteoarthritis

Sponsor: Assiut University

Sex: All·Age: 40+

Code: NCT07566520

CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry

for Psoriatic Arthritis

Sponsor: JULIO GRANADOS MONTIEL

Sex: All·Age: 18+

Code: NCT07567378

Validation of a Body-Composition Segmentation Software on a Diverse Public CT Scan Cohort

for Sarcopenia

1 site in San Francisco

Sponsor: Nucleo Research, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07600866

Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients

for Sarcopenia

Sponsor: Sichuan Provincial People's Hospital

Sex: All·Age: 18 - 80

Code: NCT07607236

Creatine Supplementation During GLP-1a Therapy

for Sarcopenia

Sponsor: University of Saskatchewan

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07625202

Apply to this trial

Clinical Relevance of Ultrasound-based Intramuscular Fat Infiltration Assessment in Hospitalized Older Adults (FATUS-OLD)

for Physical Performance Decline in Older Adults

Sponsor: Nantes University Hospital

Sex: All·Age: 75+

Code: NCT07411547

Apply to this trial

MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

for Sepsis

3 sites incl. Rochester

Sponsor: Health Discovery Labs

Sex: All·Age: 18 - 85

Code: NCT07362862

Apply to this trial

Effectiveness of RPT With Elastic Band in Tx of Sarcopenia in LTCFs

for Sarcopenia

Sponsor: Cishan Hospital, Ministry of Health and Welfare

Sex: All·Age: 60+

Code: NCT07513025

Apply to this trial

Sarcopenia in Older Patients Hospitalized for Acute Heart Failure.

for Acute Heart Failure (AHF)

Sponsor: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal

Sex: All·Age: 80+

Code: NCT07530029

Apply to this trial

Creatine Supplementation and Resistance Training to Improve Sarcopenia Parameters in Patients With Prostate Cancer After Androgen Deprivation Therapy

for Prostate Cancer

Sponsor: University of Sao Paulo

Sex: Male·Age: 40+

Code: NCT07463092

Apply to this trial

Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study

for Osteoporosis

Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Sex: All·Age: 18+

Code: NCT07677033

Apply to this trial

Personalized Cooking and Nutrition Guidance and Physical Activities Program to Reduce Muscle Loss in Advanced Cancer

for Cancer

Sponsor: Gali Perel

Sex: All·Age: 18+

Code: NCT07466862

Group Reading and Oral Exercise Program for Older Adults

for Oral Frailty

Sponsor: Mackay Memorial Hospital

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07550335

Tele-Rehabilitation in Adults With Cystic Fibrosis

for Cystic Fibrosis

Sponsor: King Saud University

Sex: All·Age: 18+

Code: NCT07500493

Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

for Cirrhosis

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07029243

Apply to this trial

Sarcopenia Indicators After Bariatric Surgery

for Obesity

Sponsor: Hatice Zehra FERHATLAR

Sex: All·Age: 18 - 65

Code: NCT07717333

Apply to this trial

TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status

for Pre-Frailty

Sponsor: Tri-Service General Hospital (TSGH)

Sex: All·Age: 65+

Code: NCT07597850·Phase 2

Apply to this trial

Health Promotion With Targeted Exercise Intervention for Decreasing Fall Risk and Inactivity in Aging Veterans With Obesity and Signs of Sarcopenia

for Falls

1 site in Baltimore

Sponsor: VA Office of Research and Development

Sex: All·Age: 55+

Code: NCT07206368

Apply to this trial

Exercise for the Treatment of Cancer-Related Sarcopenia

for Cancer

Sponsor: State University of Londrina

Sex: Female·Age: 18+

Code: NCT07498985

A Short-Bout Combined Aerobic and Resistance Exercise Program in Older Adults With Diabetes and Probable Sarcopenia

for Sarcopenia

Sponsor: Sun Yat-sen University

Sex: All·Age: 60+

Code: NCT07522359

A Randomized, Double-blind, Placebo-controlled, Prospective, Multi-center Trial Evaluating the Improvement of Nutritional Status and Sarcopenia With Silkworm Pupa Tablets in Patients With Malignancies

for Nutritional Deficiency

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: 18 - 80

Code: NCT07554807·Phase 3

Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial

for Sarcopenia

Sponsor: Gaziosmanpasa Research and Education Hospital

Sex: All·Age: 65+

Code: NCT07575958

Apply to this trial

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Sarcopenia clinical trials — common questions

Are sarcopenia clinical trials free to join?

Yes. Participating in a sarcopenia clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a sarcopenia clinical trial?

Each sarcopenia study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a sarcopenia trial near me?

Use the location controls above. We'll show recruiting sarcopenia trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many sarcopenia trials are recruiting right now?

We're currently tracking roughly 24 recruiting sarcopenia trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Sarcopenia trials by city

Cleveland, OH San Francisco, CA Birmingham, AL Columbus, OH Eugene, OR

Related specialties

Geriatrics