Clinical Trials at Lineberger Comprehensive Cancer Center
As of August 2026, 10 paid clinical trials are recruiting at Lineberger Comprehensive Cancer Center, located at UNC Lineberger Comprehensive Cancer Center LCCC, 450 West Dr, Chapel Hill, NC 27599, phone (866) 869-1856 in Chapel Hill, North Carolina. Active studies at this site cover conditions such as Breast Cancer, Multiple Myeloma and Obesity. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Chapel Hill
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
11 clinical trials at Lineberger Comprehensive Cancer Center
·Clear filters·Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Tirzepatide in Obesity-Driven Endometrial Cancer
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
Digital Art Therapy for Young Cancer Survivors
Common conditions studied in Chapel Hill
- Breast Cancer (27 active studies)
- Cancer (16 active studies)
- Multiple Myeloma (16 active studies)
- Obesity (11 active studies)
- Ulcerative Colitis (10 active studies)
- Chronic Lymphocytic Leukemia (9 active studies)
Leading research sponsors in Chapel Hill
- University of North Carolina, Chapel Hill
- UNC Lineberger Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Chapel Hill?
There are approximately 692 recruiting clinical trials in Chapel Hill, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chapel Hill pay participants?
Most recruiting trials in Chapel Hill compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chapel Hill?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chapel Hill?
The most common conditions under active study in Chapel Hill include Breast Cancer (27), Cancer (16), Multiple Myeloma (16), Obesity (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chapel Hill?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chapel Hill on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chapel Hill?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chapel Hill?
Recruiting research sites in Chapel Hill include University of North Carolina at Chapel Hill, University of North Carolina, UNC Lineberger Comprehensive Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chapel Hill right now?
The largest active categories in Chapel Hill are Cancer & tumors (241), Diabetes & metabolic (38), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Lineberger Comprehensive Cancer Center?
Lineberger Comprehensive Cancer Center is located at UNC Lineberger Comprehensive Cancer Center LCCC, 450 West Dr, Chapel Hill, NC 27599. Use the Google Maps link in the intro above to get directions.
How do I contact Lineberger Comprehensive Cancer Center?
You can reach Lineberger Comprehensive Cancer Center by phone at (866) 869-1856. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.