Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®
for Insomnia
1 location in Durham
Sponsor: Idorsia Pharmaceuticals Ltd.
Sex: Female·Age: 15 - 50
Code: NCT06498128·Recruiting
Insomnia Clinical Trials in Durham, NC
As of June 2026, 2 paid clinical trials are recruiting for Insomnia in Durham, North Carolina. Recruiting Insomnia studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Durham
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2 clinical trials for Insomnia
·Clear filters·↓ Download CSVPharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
for Coronavirus Infection (COVID-19)
49 locations incl. Phoenix
Sponsor: Duke University
Sex: All·Age: 0 - 20·Accepts healthy volunteers
Code: NCT04278404·Recruiting
About research studies in Durham
Durham has approximately 1,079 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.
Top Research Study Locations in Durham
Researchers run research studies in Durham, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke University Medical Center | Acute Myeloid Leukemia, Interstitial Lung Disease, Malignant Solid Neoplasm | 293 |
| Duke University | Heart Failure, Prostate Cancer, Breast Cancer | 200 |
| Duke University Hospital | Heart Failure, Stroke, Traumatic Brain Injury | 58 |
| Duke University Health System | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 44 |
| Duke Cancer Institute | Breast Cancer, Cancer, Ovarian Cancer | 39 |
| Duke Cancer Center | Advanced Solid Tumor, Breast Cancer, Non-small Cell Lung Cancer | 30 |
| Durham VA Medical Center, Durham, NC | Cancer, Metastatic Prostate Cancer, Posttraumatic Stress Disorder | 30 |
| Durham VA Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 19 |
| Duke Eye Center | Geographic Atrophy, Glaucoma, Stargardt Disease | 15 |
| Duke University School of Medicine | Irritable Bowel Syndrome With Constipation (IBS-C), Accidental Falls/Prevention and Control, Acute Respiratory Failure | 14 |
| Duke University Eye Center | Amblyopia, Retinal Disease, Eye Diseases | 12 |
| Duke | Acute GVHD, Acute Myelogenous Leukemia, Advanced Ovarian Carcinoma | 8 |
| Duke Health | Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias, Breast Reconstruction | 7 |
| RTI International | Alcohol Misuse, Infant, Low Birth Weight, Infant, Newborn | 7 |
| Clinical Trial Site | ATTR Amyloidosis, Cerebral Amyloid Angiopathy, Cutaneous Sarcoidosis | 6 |
| Duke Children's Hospital | Adamantinomatous Craniopharyngioma, Failed or Difficult Intubation, Sequela, Hematologic, Immune, or Bone Marrow Disorders | 6 |
| Duke University - Main Hospital and Clinics | COVID-19 Infection, Gram-negative Bacterial Infection, Healthy | 5 |
| Duke Children's Hospital & Health Center | Acute Respiratory Distress Syndrome, Analgesics, Opioid, Congenital Heart Disease (CHD) | 5 |
| Duke University Medical Center - Duke Cancer Center | Cancer of the Prostate, Colorectal Cancer, Hormone Sensitive Prostate Cancer | 5 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Colonic Neoplasms, Lung Diseases, Interstitial | 5 |
| Duke Vaccine and Trials Unit | COVID-19 Infection, Clostridioides Difficile Associated Disease, Healthy | 4 |
| Duke Lung Transplant Clinic - Clinic 2F/2G - PPDS | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| Duke Regional Hospital | Agitated Delirium, Atherosclerosis of Extremities, Delirium Confusional State | 4 |
| Duke Cancer Network | Advanced Breast Cancer, Advanced Colorectal Adenocarcinoma, Advanced Colorectal Carcinoma | 3 |
| Duke Center for Living | Diabetes (DM), Cardiac Rehabilitation, Heart Disease | 3 |
Active & Upcoming Studies in Durham (2026)
Recruiting trials in Durham grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (297 active studies)
- Vaginal Dilator Therapy After Pelvic Radiation · Duke University
- Study of Monochromatic X-ray Mammography System · Imagine Scientific, Inc.
Cardiovascular (99 active studies)
- Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) · Phase 2 · Stanford University
- A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia · Phase 1, Phase 2 · Duke University
Neurology & pain (68 active studies)
Diabetes & metabolic (29 active studies)
- Planning Grant for TOPS for Breast Cancer Survivors · Duke University
- Studies of Insulin and Glucagon Action in the Liver · Phase 1, Phase 2 · Duke University
Pediatric (29 active studies)
- Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children · Duke University
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
Mental health & behavior (18 active studies)
- Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms · VA Office of Research and Development
- The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · Duke University
HIV / STI (13 active studies)
- NOTRE: Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings · Phase 4 · Duke University
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
Eye & vision (12 active studies)
- Advancing Pediatric Retinal Imaging With Auto-aligned OCT · Duke University
- Automated Applanation Tonometry - Updated · Duke University
Vaccines (8 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- pH1N1 Blinded Challenge Study · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Durham
- Heart Failure (22 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Breast Cancer (20 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (16 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Cancer (13 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Multiple Myeloma (12 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (11 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
Leading research sponsors in Durham
- Duke University
- National Cancer Institute (NCI)
- VA Office of Research and Development
- AstraZeneca
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Durham. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Durham
Hipa.ai aggregates every recruiting study in Durham from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Durham?
There are approximately 1,079 recruiting clinical trials in Durham, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Durham pay participants?
Most recruiting trials in Durham compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Durham?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Durham?
The most common conditions under active study in Durham include Heart Failure (22), Breast Cancer (20), Prostate Cancer (16), Cancer (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Durham?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Durham on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Durham?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Durham?
Recruiting research sites in Durham include Duke University Medical Center, Duke University, Duke University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Durham right now?
The largest active categories in Durham are Cancer & tumors (297), Cardiovascular (99), Neurology & pain (68). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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