Paid Clinical Trials in Philadelphia, PA

As of July 2026, 1,980 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Philadelphia offers studies at sites including University of Pennsylvania for conditions such as Breast Cancer, Prostate Cancer, Ovarian Cancer, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Philadelphia

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Top Research Study Locations in Philadelphia

Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
University of PennsylvaniaHeart Failure, Opioid Use Disorder, Cardiovascular Diseases351
Children's Hospital of PhiladelphiaHigh Grade Glioma, Diffuse Intrinsic Pontine Glioma, Pediatric Cancer305
Thomas Jefferson University HospitalAcute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8111
Thomas Jefferson UniversityFocal Epilepsy, Advanced Melanoma, Cancer97
Fox Chase Cancer CenterBreast Cancer, Cancer, Urothelial Carcinoma94
Hospital of the University of PennsylvaniaAbdominal Aortic Aneurysm, Breast Cancer, Obstetrical Complications89
The Children's Hospital of PhiladelphiaEosinophilic Esophagitis (EoE), Mitochondrial Diseases, Primary Mitochondrial Disease44
Temple UniversityCOPD, Amyotrophic Lateral Sclerosis, Emphysema39
Temple University HospitalInterstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis38
University of Pennsylvania/Abramson Cancer CenterAcute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy30
Penn Presbyterian Medical CenterAtrial Fibrillation, Heart Failure, ADHF28
Pennsylvania HospitalStroke, Acute, Activity Restriction, Advanced Cancer28
Abramson Cancer Center of the University of PennsylvaniaBreast Cancer, Advanced Solid Tumor, DLBCL - Diffuse Large B Cell Lymphoma26
Saint Christopher's Hospital for ChildrenMalignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia23
Jefferson Torresdale HospitalAnatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v822
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PAParkinson Disease, Stress Disorders, Post-Traumatic, Alcohol Use Disorder18
Sidney Kimmel Cancer Center at Thomas Jefferson UniversityColorectal Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v815
Drexel UniversityAutism Spectrum Disorder, Obesity, Anxiety13
Penn MedicineHypertension, ALS, Allogeneic Transplantation12
University of Pennsylvania Health SystemBehavior, Health, Acute Kidney Injury, Atrial Fibrillation12
University of Pennsylvania HospitalChronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma12
University of Pennsylvania, Abramson Cancer CenterAdvanced Solid Tumor, Biliary Tract Cancer, Breast Cancer12
GSK Investigational SiteAsthma, Connective Tissue Diseases, Gastrointestinal Neoplasms11
Childrens Hospital of PhiladelphiaSuicide, Chronic Kidney Disease, Depression11
Thomas Jefferson University, Sidney Kimmel Cancer CenterAdvanced Solid Tumor, Colorectal Cancer, Bladder Cancer11

Active & Upcoming Studies in Philadelphia (2026)

Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cancer & tumors (556 active studies)

Neurology & pain (110 active studies)

Vaccines (6 active studies)

Common conditions studied in Philadelphia

Leading research sponsors in Philadelphia

  • University of Pennsylvania
  • Abramson Cancer Center at Penn Medicine
  • Children's Hospital of Philadelphia
  • Thomas Jefferson University
  • National Cancer Institute (NCI)

Frequently asked questions

How many paid clinical trials are currently recruiting in Philadelphia?

There are approximately 1,980 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Philadelphia pay participants?

Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Philadelphia?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Philadelphia?

The most common conditions under active study in Philadelphia include Breast Cancer (35), Cancer (24), Prostate Cancer (22), Ovarian Cancer (21), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Philadelphia?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Philadelphia?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Philadelphia?

Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Philadelphia right now?

The largest active categories in Philadelphia are Cancer & tumors (556), Neurology & pain (110), Cardiovascular (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Related healthcare resources in Pennsylvania

Trials by condition in Philadelphia