Paid Clinical Trials in Philadelphia, PA
As of July 2026, 1,980 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Philadelphia offers studies at sites including University of Pennsylvania for conditions such as Breast Cancer, Prostate Cancer, Ovarian Cancer, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Philadelphia
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·Clear filters·↓ Download CSVTop Research Study Locations in Philadelphia
Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pennsylvania | Heart Failure, Opioid Use Disorder, Cardiovascular Diseases | 351 |
| Children's Hospital of Philadelphia | High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Pediatric Cancer | 305 |
| Thomas Jefferson University Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 111 |
| Thomas Jefferson University | Focal Epilepsy, Advanced Melanoma, Cancer | 97 |
| Fox Chase Cancer Center | Breast Cancer, Cancer, Urothelial Carcinoma | 94 |
| Hospital of the University of Pennsylvania | Abdominal Aortic Aneurysm, Breast Cancer, Obstetrical Complications | 89 |
| The Children's Hospital of Philadelphia | Eosinophilic Esophagitis (EoE), Mitochondrial Diseases, Primary Mitochondrial Disease | 44 |
| Temple University | COPD, Amyotrophic Lateral Sclerosis, Emphysema | 39 |
| Temple University Hospital | Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis | 38 |
| University of Pennsylvania/Abramson Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 30 |
| Penn Presbyterian Medical Center | Atrial Fibrillation, Heart Failure, ADHF | 28 |
| Pennsylvania Hospital | Stroke, Acute, Activity Restriction, Advanced Cancer | 28 |
| Abramson Cancer Center of the University of Pennsylvania | Breast Cancer, Advanced Solid Tumor, DLBCL - Diffuse Large B Cell Lymphoma | 26 |
| Saint Christopher's Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 23 |
| Jefferson Torresdale Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 22 |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Parkinson Disease, Stress Disorders, Post-Traumatic, Alcohol Use Disorder | 18 |
| Sidney Kimmel Cancer Center at Thomas Jefferson University | Colorectal Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 15 |
| Drexel University | Autism Spectrum Disorder, Obesity, Anxiety | 13 |
| Penn Medicine | Hypertension, ALS, Allogeneic Transplantation | 12 |
| University of Pennsylvania Health System | Behavior, Health, Acute Kidney Injury, Atrial Fibrillation | 12 |
| University of Pennsylvania Hospital | Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma | 12 |
| University of Pennsylvania, Abramson Cancer Center | Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer | 12 |
| GSK Investigational Site | Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms | 11 |
| Childrens Hospital of Philadelphia | Suicide, Chronic Kidney Disease, Depression | 11 |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer | 11 |
Active & Upcoming Studies in Philadelphia (2026)
Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (556 active studies)
- The AYA Oncology Self-care Movement · Northwestern University
- PICSTAT Pilot Study for CD8 PET/CT-Guided Lifileucel Treatment in Advanced Melanoma · EARLY_Phase 1 · Abramson Cancer Center at Penn Medicine
Neurology & pain (110 active studies)
- Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease · Phase 4 · VA Office of Research and Development
- Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA · Geisinger Clinic
Cardiovascular (105 active studies)
Diabetes & metabolic (65 active studies)
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Pediatric (49 active studies)
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
- Bilevel Positive Airway Pressure (BPAP) for Severe Asthma · Columbia University
Mental health & behavior (47 active studies)
- NST-SPARK Open-Label Phase 1 STTR (IGNITE) · North Shore Therapeutics, Inc.
- Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System · Temple University
HIV / STI (24 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System · Temple University
Eye & vision (22 active studies)
- Penn SICCA Follow-up Study · University of Pennsylvania
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Vaccines (6 active studies)
- Flu Infection at UPHS · University of Pennsylvania
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
Common conditions studied in Philadelphia
- Breast Cancer (35 active studies)
- Cancer (24 active studies)
- Prostate Cancer (22 active studies)
- Ovarian Cancer (21 active studies)
- Heart Failure (20 active studies)
- Advanced Solid Tumor (18 active studies)
Leading research sponsors in Philadelphia
- University of Pennsylvania
- Abramson Cancer Center at Penn Medicine
- Children's Hospital of Philadelphia
- Thomas Jefferson University
- National Cancer Institute (NCI)
Frequently asked questions
How many paid clinical trials are currently recruiting in Philadelphia?
There are approximately 1,980 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Philadelphia pay participants?
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Philadelphia?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Philadelphia?
The most common conditions under active study in Philadelphia include Breast Cancer (35), Cancer (24), Prostate Cancer (22), Ovarian Cancer (21), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Philadelphia?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Philadelphia?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Philadelphia?
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Philadelphia right now?
The largest active categories in Philadelphia are Cancer & tumors (556), Neurology & pain (110), Cardiovascular (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.