Paid Clinical Trials in Pittsburgh, PA
As of July 2026, 1,239 paid clinical trials are recruiting in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Pittsburgh offers studies at sites including University of Pittsburgh for conditions such as Breast Cancer, Melanoma, Stroke, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Pittsburgh
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1 clinical trial
·Clear filters·↓ Download CSVTop Research Study Locations in Pittsburgh
Researchers run research studies in Pittsburgh, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pittsburgh | Stroke, Traumatic Brain Injury, Dementia | 159 |
| University of Pittsburgh Medical Center | Chronic Pancreatitis, Cystic Fibrosis, Advanced Solid Tumor | 131 |
| University of Pittsburgh Cancer Institute (UPCI) | Metastatic Malignant Solid Neoplasm, Acute Myeloid Leukemia, Unresectable Malignant Solid Neoplasm | 87 |
| UPMC Hillman Cancer Center | Melanoma, Hepatocellular Carcinoma, Glioma | 79 |
| Allegheny General Hospital | Breast Cancer, Anatomic Stage II Breast Cancer AJCC v8, Pulmonary Hypertension | 64 |
| Children's Hospital of Pittsburgh of UPMC | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia | 61 |
| UPMC Children's Hospital of Pittsburgh | Fabry Disease, Cerebral Palsy, Congenital Bone Marrow Failure Syndromes | 51 |
| UPMC-Passavant Hospital | Anatomic Stage II Breast Cancer AJCC v8, Recurrent Endometrial Carcinoma, Stage IV Lung Cancer AJCC v8 | 35 |
| Allegheny Health Network | Brain Tumor, Breast Cancer, Multiple Myeloma | 30 |
| UPMC-Saint Clair Hospital Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Head and Neck Squamous Cell Carcinoma, Stage III Laryngeal Cancer AJCC v8 | 29 |
| UPMC-Saint Margaret | Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8, Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | 26 |
| UPMC-Magee Womens Hospital | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Recurrent Endometrial Carcinoma | 23 |
| West Penn Hospital | Large B-cell Lymphoma, Stage IV Colorectal Cancer AJCC v8, Acute Lymphoblastic Leukemia (ALL) | 23 |
| UPMC-Shadyside Hospital | Head and Neck Squamous Cell Carcinoma, Metastatic Renal Cell Carcinoma, Stage II Lip and Oral Cavity Cancer AJCC v8 | 22 |
| UPMC | Focal Epilepsy, ASD - Atrial Septal Defect, Advanced Melanoma | 21 |
| UPMC Presbyterian | Acute Kidney Injuries, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 19 |
| VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA | Cardiovascular Diseases, Stroke, Acute Kidney Injury | 19 |
| UPMC Presbyterian Hospital | Abdominal Surgery, Acute Ischemic Stroke, Acute Myocardial Infarction | 18 |
| Children's Hospital of Pittsburgh | Diabetes Mellitus, Type 2, Hyperglycemia, Physical Inactivity | 17 |
| UPMC Magee-Womens Hospital | ADHD, Behavioral Intervention, Breast Cancer | 9 |
| University of Pittsburgh School of Medicine | Adolescents, Anorexia Nervosa, Bipolar Disorder (BD) | 9 |
| AHN Allegheny General Hospital | Breast Cancer, Cancer, Carcinoma, Non-Small-Cell Lung | 8 |
| University of Pittsburgh Medical Center (UPMC) | ALS, ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis | 8 |
| AHN West Penn Hospital | Malignant Mesothelioma, Malignant Pleural Effusion, Metastasis to Pleura | 7 |
| UPMC Shadyside Hospital | Abdominal Surgery, Dementia, Harm Reduction | 7 |
Active & Upcoming Studies in Pittsburgh (2026)
Recruiting trials in Pittsburgh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (400 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma · Phase 1 · National Cancer Institute (NCI)
Neurology & pain (84 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- NEUROCUPLE™ as an Opioid Alternative Following Total Knee Arthroplasty · Jacques E. Chelly
Cardiovascular (69 active studies)
- Prediction and Prevention of Postoperative Mortality and Morbidity · University of Pittsburgh
- TEPH: Telaglenastat Efficacy in Pulmonary Hypertension · Phase 1, Phase 2 · Chan, Stephen, MD, PhD
Mental health & behavior (38 active studies)
- Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · University of Pittsburgh
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
Diabetes & metabolic (36 active studies)
- Technology Knowledge Optimization for Type 1 Diabetes in Schools · University of Pittsburgh
- Real-time Engagement for Learning to Effectively Control Type 2 Diabetes · University of Pittsburgh
Pediatric (18 active studies)
- A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients · Phase 2 · Costas Hadjipanayis
- Caregiver-Adolescent Dating Violence Prevention Intervention Pilot Trial · University of Pittsburgh
HIV / STI (9 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System · University of Pittsburgh
Vaccines (8 active studies)
- A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine · Phase 3 · Pfizer
- A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant · Phase 2 · GlaxoSmithKline
Eye & vision (3 active studies)
- A Study to Learn How Stargardt-type Eye Conditions Progress in Children and Adults · Astellas Pharma Global Development, Inc.
- The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease · Rinsada
Common conditions studied in Pittsburgh
- Breast Cancer (25 active studies)
- Cancer (18 active studies)
- Melanoma (18 active studies)
- Stroke (17 active studies)
- Endometrial Cancer (16 active studies)
- Ovarian Cancer (15 active studies)
Leading research sponsors in Pittsburgh
- University of Pittsburgh
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Pittsburgh?
There are approximately 1,239 recruiting clinical trials in Pittsburgh, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Pittsburgh pay participants?
Most recruiting trials in Pittsburgh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Pittsburgh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Pittsburgh?
The most common conditions under active study in Pittsburgh include Breast Cancer (25), Cancer (18), Melanoma (18), Stroke (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Pittsburgh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pittsburgh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Pittsburgh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Pittsburgh?
Recruiting research sites in Pittsburgh include University of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh Cancer Institute (UPCI), among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Pittsburgh right now?
The largest active categories in Pittsburgh are Cancer & tumors (400), Neurology & pain (84), Cardiovascular (69). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.