Mild cognitive impairment (MCI) Clinical Trials

Recruiting mild cognitive impairment (mci) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat mild cognitive impairment (mci). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting mild cognitive impairment (mci) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting mild cognitive impairment (mci) trials

Within

Gaze and Gait Training With rTMS

for Mild Cognitive Impairment

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT05864313

Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog

for Mild Cognitive Impairment

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 50+

Code: NCT06542458

(MAP) Pilot Randomized Controlled Trial for Older Adults With Mild Cognitive Impairment and Elevated Stress

for Mild Cognitive Impairment (MCI)

Sponsor: Rush University Medical Center

Sex: All·Age: 65+

Code: NCT07389655

Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns

for Subjective Cognitive Decline (SCD)

Sponsor: Johns Hopkins University

Sex: All·Age: 65+

Code: NCT07440498

Multicomponent Intervention to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: City University of Hong Kong

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07549074

Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables

for Active Aging Individuals Aged 65 and Over

Sponsor: Neuromed IRCCS

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07533084

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

for Mild Cognitive Impairment (MCI)

1 site in Palisades Park

Sponsor: Noah Tech, Corp.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07214974·EARLY_Phase 1

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2

for Mild Cognitive Impairment

3 sites incl. Tallahassee

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07485712

An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

for Mild Cognitive Impairment (MCI)

1 site in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07127133

Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 site in The Bronx

Sponsor: Albert Einstein College of Medicine

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07225400

Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns

for Subjective Cognitive Decline

Sponsor: IRCCS San Raffaele

Sex: All·Age: 40+

Code: NCT07652931

LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement

for Mild Cognitive Impairment

Sponsor: George Mason University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07685067

Superior Parietal iTBS for PD-MCI

for Parkinson Disease

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 50 - 85

Code: NCT07701785

Apply to this trial

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 1

for Mild Cognitive Impairment

3 sites incl. Tallahassee

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05811338

Assessment of Motor Reserve in the Preclinical Stages of Dementia

for Mild Cognitive Impairment (MCI)

Sponsor: Istituto per la Ricerca e l'Innovazione Biomedica

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07634055

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Effects of Functional Oils on Obesity With Mild Cognitive Impairment

for Obesity

Sponsor: Capital Medical University

Sex: All·Age: 45 - 75

Code: NCT07690384

Mild Cognitive Impairment and Neuromodulation

for Mild Cognitive Impairment (MCI)

1 site in Roanoke

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 55 - 80

Code: NCT07691918

AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults

for Mild Cognitive Impairment (MCI)

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 75+

Code: NCT07701668

Non-pharmacological Interventions for People With Mild Cognitive Impairment in the Community

for Mild Cognitive Impairment (MCI)

Sponsor: Anhui Medical University

Sex: All·Age: 60+

Code: NCT07703267

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

for Alzheimer s Disease

1 site in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT07169630·Phase 1

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Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Posit Science Corporation

Sex: All·Age: 65+

Code: NCT07243600

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Digital Lifestyle Coaching for Alzheimer's Disease Prevention in APOE4 Carriers

for Mild Cognitive Impairment (MCI)

1 site in La Jolla

Sponsor: Scripps Translational Science Institute

Sex: All·Age: 60 - 80

Code: NCT07646054

EVASION: Effect of VisuAl Stimulation on attentION

for Mild Cognitive Impairment

Sponsor: University Hospital, Angers

Sex: All·Age: 60+

Code: NCT05791994

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Implementation of AIP Services for Older Adults With AD

for Alzheimer Disease

1 site in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07361601

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

for Insomnia

1 site in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07397182

Enhancing Attention in Elderly Using a Brain-Computer-Interface

for Mild Cognitive Impairment (MCI)

1 site in Austin

Sponsor: University of Texas at Austin

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07441122

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Optimising Exercise to Improve Physical and Cognitive Frailty in Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Universiti Sains Malaysia

Sex: All·Age: 60 - 85

Code: NCT07600034

The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI

for Mild Cognitive Impairment (MCI)

Sponsor: qiu chen

Sex: All·Age: 60 - 74

Code: NCT07656480

Effects of Ginkgo Biloba on Blood Biomarkers in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Hanyang University

Sex: All·Age: 20+

Code: NCT07579689·Phase 4

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

for Mild Cognitive Impairment (MCI)

1 site in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 55 - 80

Code: NCT07583251·Phase 1

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Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients

for Post-stroke

Sponsor: Marta Mondellini

Sex: All·Age: 18+

Code: NCT07616050

Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational Rehabilitation

for Stroke

Sponsor: University of Pavia

Sex: All·Age: 18 - 80

Code: NCT07636538

An AI-Based Prediction of Cognitive Capacity in Older Adults and Individuals With Mild Cognitive Impairment During Virtual Reality Driving Tasks

for Mild Cognitive Impairment (MCI)

Sponsor: National Cheng-Kung University Hospital

Sex: All·Age: 30 - 85

Code: NCT07656389

Feasibility, Usability, and Acceptability of Virtual Reality-Based Cognitive and Physical Rehabilitation in Individuals With Mild Cognitive Impairment

for Mild Cognitive Impairment

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 55 - 90

Code: NCT07638748

Sensory Enrichment Using Aromatherapy for Neurobehavioral and Psychological Symptoms in Early Dementia

for Mild Cognitive Impairment

Sponsor: National Cancer Centre, Singapore

Sex: All·Age: 50 - 99

Code: NCT07234357

Apply to this trial

Music for Pain and Dementia

for Alzheimer Disease

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT07602283

Apply to this trial

Light and Sleep Fragmentation

for Sleep

1 site in Redwood City

Sponsor: Stanford University

Sex: All·Age: 65 - 99·Accepts healthy volunteers

Code: NCT06009289·Phase 4

Neuromodulation and fMRI in Neurodegenerative Diseases Study

for Mild Cognitive Impairment

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: 25+·Accepts healthy volunteers

Code: NCT06873750

Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)

for Dementia (Diagnosis)

Sponsor: Zealand University Hospital

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07200739

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

for Osteoarthritis (OA) of the Hip

1 site in Fairway

Sponsor: University of Kansas Medical Center

Sex: All·Age: 55 - 75

Code: NCT07417891

Percepta for Cognitive Optimization

for Mild Cognitive Impairment (MCI)

1 site in Wilmington

Sponsor: Cerebrum DAO Association

Sex: All·Age: 40 - 85

Code: NCT07612449

The Cognitive Protective Effect of VR-based Cognitive Training in Type 2 Diabetes Patients With Mild Cognitive Impairment

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 45 - 80

Code: NCT07650318

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Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease

for Alzheimer Disease (AD)

1 site in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT07659964

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To Evaluate the Safety and Efficacy of RP902 Tablets

for Mild Cognitive Impairment (MCI)

Sponsor: Risen (Suzhou) Pharma Tech Co., Ltd.

Sex: All·Age: 50 - 85

Code: NCT07579884·Phase 2

Telehealth-Adapted Compensatory Training and Intervention for Cognition

for MCI

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 65 - 84

Code: NCT07366346

Apply to this trial

Transcutaneous Auricular Vagus Nerve Stimulation in Type 2 Diabetes With Mild Cognitive Impairment

for Type 2 Diabetes

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 40 - 75

Code: NCT07642518

Crownlands Observing Progression With Neurons Study

for Alzheimer s Disease

1 site in Germantown

Sponsor: Crownlands

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07611396

Apply to this trial

Expanding Access to Cognitive Health Biomarker Testing at Home

for Mild Cognitive Impairment (MCI)

1 site in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 65+

Code: NCT07594665

Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early Alzheimer's Disease.

for Mild Cognitive Impairment

1 site in Miami

Sponsor: Bernard (Barry) Baumel

Sex: All·Age: 55 - 90

Code: NCT07512362·Phase 2

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Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study

for Mild Cognitive Impairment (MCI)

Sponsor: Lidian Chen

Sex: All·Age: 60+

Code: NCT07608510

The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia

for Dementia Prevention

Sponsor: University of British Columbia

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07364019

Apply to this trial

Digital Tools to Support Healthcare Decision Making

for Mild Cognitive Impairment

2 sites incl. Champaign

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07485725

Apply to this trial

Improving Dementia Care in Primary Practice

for Alzheimer Disease (AD)

Sponsor: Thomas Jefferson University

Sex: All·Age: 66+·Accepts healthy volunteers

Code: NCT07526480

Making Antibody Treatments More Effective in Early Alzheimer's Disease Using 3Tesla Magnetica Resonance

for Alzheimer Dementia (AD)

Sponsor: IRCCS San Raffaele

Sex: All·Age: 30 - 90

Code: NCT07456462

Community-based Screening for Alzheimer's Disease

for Alzheimer's Disease(AD)

Sponsor: Kuang XiaoJun

Sex: All·Age: 60 - 80·Accepts healthy volunteers

Code: NCT07570719

Apply to this trial

Mindfulness With Dual-Task Training in Post-Stroke Mild Cognitive Impairment

for Stroke

Sponsor: Nanjing Mingzhou Rehabilitation Hospital

Sex: All·Age: 55+

Code: NCT07603102

Apply to this trial

The Effect of Body Percussion Training on Neuromotor Performance, Attention, and Functionality in Adolescents With Mild Intellectual Disability

for Mild Cognitive Impairment

Sponsor: Kutahya Health Sciences University

Sex: All·Age: 14 - 19

Code: NCT07554144

Auditory Sleep Stimulation or Sham in People With Parkinson Disease Mild Cognitive Impairment During Cognitive Training

for Parkinson's Disease

Sponsor: University of Zurich

Sex: All·Age: 18+

Code: NCT07441915

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A Comparison of the Efficacy of Different Rehabilitation Strategies in Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Istanbul University - Cerrahpasa

Sex: All·Age: 65+

Code: NCT07547111

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

for Dementia

1 site in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07454824

Apply to this trial

Mild cognitive impairment (MCI) clinical trials — common questions

Are mild cognitive impairment (mci) clinical trials free to join?

Yes. Participating in a mild cognitive impairment (mci) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a mild cognitive impairment (mci) clinical trial?

Each mild cognitive impairment (mci) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a mild cognitive impairment (mci) trial near me?

Use the location controls above. We'll show recruiting mild cognitive impairment (mci) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many mild cognitive impairment (mci) trials are recruiting right now?

We're currently tracking roughly 159 recruiting mild cognitive impairment (mci) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Mild cognitive impairment (MCI) trials by city

Boston, MA San Francisco, CA Chicago, IL Miami, FL San Diego, CA Los Angeles, CA Sacramento, CA Tallahassee, FL Ann Arbor, MI Aurora, CO Columbus, OH Evanston, IL

Related specialties

Neurology Dementia care Brain disorders Geriatrics