Mild cognitive impairment (MCI) Clinical Trials

Recruiting mild cognitive impairment (mci) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat mild cognitive impairment (mci). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting mild cognitive impairment (mci) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting mild cognitive impairment (mci) trials

Within

cMIND AI Web Tool Usability Study (Hong Kong)

for Mild Cognitive Impairment (MCI)

Sponsor: Hong Kong Metropolitan University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07735013

Gaze and Gait Training With rTMS

for Mild Cognitive Impairment

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT05864313

Wearable Sensor for Early Detection and Monitoring of Cognitive Decline

for Mild Cognitive Impairment (MCI)

1 site in Los Angeles

Sponsor: BioSensics

Sex: All·Age: 55+

Code: NCT07780162

Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog

for Mild Cognitive Impairment

1 site in Columbus

Sponsor: Ohio State University

Sex: All·Age: 50+

Code: NCT06542458

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

for Insomnia

1 site in San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT07397182

Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)

for Dementia (Diagnosis)

Sponsor: Zealand University Hospital

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07200739

A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement

for Memory Disorders

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07773493

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 1

for Mild Cognitive Impairment

3 sites incl. Tallahassee

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05811338

(MAP) Pilot Randomized Controlled Trial for Older Adults With Mild Cognitive Impairment and Elevated Stress

for Mild Cognitive Impairment (MCI)

Sponsor: Rush University Medical Center

Sex: All·Age: 65+

Code: NCT07389655

Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns

for Subjective Cognitive Decline (SCD)

Sponsor: Johns Hopkins University

Sex: All·Age: 65+

Code: NCT07440498

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 2

for Mild Cognitive Impairment

3 sites incl. Tallahassee

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07485712

Mild Cognitive Impairment and Neuromodulation

for Mild Cognitive Impairment (MCI)

1 site in Roanoke

Sponsor: Virginia Polytechnic Institute and State University

Sex: All·Age: 55 - 80

Code: NCT07691918

Medication Self-Management Technology for Older Adults

for Mild Cognitive Impairment (MCI)

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 60+

Code: NCT07754994

Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT

for Chronic Pain

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 120·Accepts healthy volunteers

Code: NCT07785648

Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 site in The Bronx

Sponsor: Albert Einstein College of Medicine

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07225400

Multicomponent Intervention to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: City University of Hong Kong

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07549074

AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults

for Mild Cognitive Impairment (MCI)

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 75+

Code: NCT07701668

Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables

for Active Aging Individuals Aged 65 and Over

Sponsor: Neuromed IRCCS

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07533084

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

for Alzheimer s Disease

1 site in Bethesda

Sponsor: National Institute of Mental Health (NIMH)

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT07169630·Phase 1

Apply to this trial

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

for Alzheimer Disease

1 site in Nashville

Sponsor: MTI Biotech Inc

Sex: All·Age: 55 - 85

Code: NCT06432166·Phase 1, Phase 2

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

for Mild Cognitive Impairment (MCI)

1 site in Palisades Park

Sponsor: Noah Tech, Corp.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07214974·EARLY_Phase 1

Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity

for Mild Cognitive Impairment (MCI)

1 site in Augusta

Sponsor: Augusta University

Sex: All·Age: 50 - 70

Code: NCT07741773

Temporal Interference Stimulation Combined With Tai Chi for Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Shanghai University of Sport

Sex: All·Age: 60 - 80

Code: NCT07799584

Apply to this trial

High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Istinye University

Sex: All·Age: 65 - 85

Code: NCT07762235

Alzheimer's Disease Research Center (ADRC) PET Component Study

for Alzheimer Disease

1 site in New York

Sponsor: Patrick Lao

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07758660·Phase 2

Safety And Tolerability Of Gamma Glutamylcysteine (GGC) Oral Supplementation In MCI Patients

for Mild Cognitive Impairment (MCI)

1 site in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 55 - 80

Code: NCT07583251·Phase 1

Apply to this trial

Cognitive Intervention for Cognitive Impairment

for Cognitive Intervention

Sponsor: Instituto Mexicano del Seguro Social

Sex: All·Age: 65 - 95

Code: NCT07747675

An Insole and Ankle Device for Monitoring Cognitive Decline in Individuals at Risk for Alzheimer's Disease and/or Alzheimer's Disease Related Dementias (AD/ADRD)

for Mild Cognitive Impairment (MCI)

1 site in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07127133

Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns

for Subjective Cognitive Decline

Sponsor: IRCCS San Raffaele

Sex: All·Age: 40+

Code: NCT07652931

LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement

for Mild Cognitive Impairment

Sponsor: George Mason University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07685067

Superior Parietal iTBS for PD-MCI

for Parkinson Disease

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 50 - 85

Code: NCT07701785

Apply to this trial

To Evaluate the Safety and Efficacy of RP902 Tablets

for Mild Cognitive Impairment (MCI)

Sponsor: Risen (Suzhou) Pharma Tech Co., Ltd.

Sex: All·Age: 50 - 85

Code: NCT07579884·Phase 2

Assessment of Motor Reserve in the Preclinical Stages of Dementia

for Mild Cognitive Impairment (MCI)

Sponsor: Istituto per la Ricerca e l'Innovazione Biomedica

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07634055

Apply to this trial

Effects of Functional Oils on Obesity With Mild Cognitive Impairment

for Obesity

Sponsor: Capital Medical University

Sex: All·Age: 45 - 75

Code: NCT07690384

Hippocampal Temporal Interference Stimulation for Memory and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Shanghai University of Sport

Sex: All·Age: 65+

Code: NCT07771036

Apply to this trial

Non-pharmacological Interventions for People With Mild Cognitive Impairment in the Community

for Mild Cognitive Impairment (MCI)

Sponsor: Anhui Medical University

Sex: All·Age: 60+

Code: NCT07703267

Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Posit Science Corporation

Sex: All·Age: 65+

Code: NCT07243600

Apply to this trial

Digital Lifestyle Coaching for Alzheimer's Disease Prevention in APOE4 Carriers

for Mild Cognitive Impairment (MCI)

1 site in La Jolla

Sponsor: Scripps Translational Science Institute

Sex: All·Age: 60 - 80

Code: NCT07646054

EVASION: Effect of VisuAl Stimulation on attentION

for Mild Cognitive Impairment

Sponsor: University Hospital, Angers

Sex: All·Age: 60+

Code: NCT05791994

Apply to this trial

Implementation of AIP Services for Older Adults With AD

for Alzheimer Disease

1 site in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07361601

Enhancing Attention in Elderly Using a Brain-Computer-Interface

for Mild Cognitive Impairment (MCI)

2 sites incl. Austin

Sponsor: University of Texas at Austin

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT07441122

Apply to this trial

Optimising Exercise to Improve Physical and Cognitive Frailty in Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Universiti Sains Malaysia

Sex: All·Age: 60 - 85

Code: NCT07600034

The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI

for Mild Cognitive Impairment (MCI)

Sponsor: qiu chen

Sex: All·Age: 60 - 74

Code: NCT07656480

Effects of Ginkgo Biloba on Blood Biomarkers in Mild Cognitive Impairment

for Mild Cognitive Impairment

Sponsor: Hanyang University

Sex: All·Age: 20+

Code: NCT07579689·Phase 4

Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients

for Post-stroke

Sponsor: Marta Mondellini

Sex: All·Age: 18+

Code: NCT07616050

Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational Rehabilitation

for Stroke

Sponsor: University of Pavia

Sex: All·Age: 18 - 80

Code: NCT07636538

Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment

for Mild Cognitive Impairment (MCI)

Sponsor: Shifa Tameer-e-Millat University

Sex: All·Age: 55 Months - 85 Months·Accepts healthy volunteers

Code: NCT07775079

Apply to this trial

Digital Solutions for Predicting the Biological Mechanisms of Alzheimer's Disease Through the Analysis of Risk Factors

for Mild Cognitive Impairment (MCI)

Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli

Sex: All·Age: 18+

Code: NCT07731191

Apply to this trial

An AI-Based Prediction of Cognitive Capacity in Older Adults and Individuals With Mild Cognitive Impairment During Virtual Reality Driving Tasks

for Mild Cognitive Impairment (MCI)

Sponsor: National Cheng-Kung University Hospital

Sex: All·Age: 30 - 85

Code: NCT07656389

Feasibility, Usability, and Acceptability of Virtual Reality-Based Cognitive and Physical Rehabilitation in Individuals With Mild Cognitive Impairment

for Mild Cognitive Impairment

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 55 - 90

Code: NCT07638748

Apply to this trial

Binaural Beats for Cognitive Function in Older Adults With Mild Cognitive Impairment in Nursing Homes

for Mild Cognitive Impairment

Sponsor: China Medical University, China

Sex: All·Age: 60+

Code: NCT07735910

Apply to this trial

Sensory Enrichment Using Aromatherapy for Neurobehavioral and Psychological Symptoms in Early Dementia

for Mild Cognitive Impairment

Sponsor: National Cancer Centre, Singapore

Sex: All·Age: 50 - 99

Code: NCT07234357

Apply to this trial

Music for Pain and Dementia

for Alzheimer Disease

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT07602283

Apply to this trial

Light and Sleep Fragmentation

for Sleep

1 site in Redwood City

Sponsor: Stanford University

Sex: All·Age: 65 - 99·Accepts healthy volunteers

Code: NCT06009289·Phase 4

Neuromodulation and fMRI in Neurodegenerative Diseases Study

for Mild Cognitive Impairment

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: 25+·Accepts healthy volunteers

Code: NCT06873750

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

for Osteoarthritis (OA) of the Hip

1 site in Fairway

Sponsor: University of Kansas Medical Center

Sex: All·Age: 55 - 75

Code: NCT07417891

Percepta for Cognitive Optimization

for Mild Cognitive Impairment (MCI)

1 site in Wilmington

Sponsor: Cerebrum DAO Association

Sex: All·Age: 40 - 85

Code: NCT07612449

The Cognitive Protective Effect of VR-based Cognitive Training in Type 2 Diabetes Patients With Mild Cognitive Impairment

for Type 2 Diabetes Mellitus (T2DM)

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 45 - 80

Code: NCT07650318

Apply to this trial

Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease

for Alzheimer Disease (AD)

1 site in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT07659964

Apply to this trial

Telehealth-Adapted Compensatory Training and Intervention for Cognition

for MCI

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 65 - 84

Code: NCT07366346

Apply to this trial

New trials in Boston, MA?

Pick a condition and we'll email you once a week when a new study starts recruiting in Boston, MA. Unsubscribe anytime.

Mild cognitive impairment (MCI) clinical trials — common questions

Are mild cognitive impairment (mci) clinical trials free to join?

Yes. Participating in a mild cognitive impairment (mci) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a mild cognitive impairment (mci) clinical trial?

Each mild cognitive impairment (mci) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a mild cognitive impairment (mci) trial near me?

Use the location controls above. We'll show recruiting mild cognitive impairment (mci) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many mild cognitive impairment (mci) trials are recruiting right now?

We're currently tracking roughly 159 recruiting mild cognitive impairment (mci) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Mild cognitive impairment (MCI) trials by city

Boston, MA San Francisco, CA Chicago, IL Miami, FL San Diego, CA Sacramento, CA Tallahassee, FL Ann Arbor, MI Aurora, CO Columbus, OH Evanston, IL Los Angeles, CA

Related specialties

Neurology Dementia care Brain disorders Geriatrics