Preeclampsia Clinical Trials

Recruiting preeclampsia studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat preeclampsia. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting preeclampsia studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting preeclampsia trials

Within

Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention

for Preeclampsia

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT07614893

Use of Allied-health Professionals to Improve Treatment of Disease

for Preeclampsia

Sponsor: University of Iowa

Sex: Female·Age: 18 - 55

Code: NCT06337799

Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth

for Preterm Birth

Sponsor: Odense University Hospital

Sex: Female·Age: 18+

Code: NCT07191366

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

for Preeclampsia

1 site in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18 - 50

Code: NCT06333652·Phase 2

Apply to this trial

Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy

for Pregnancy

Sponsor: University of Salamanca

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07656532

Identification of Genes of Interest for Severe Forms of Preeclampsia

for Preeclampsia

Sponsor: University Hospital, Strasbourg, France

Sex: Female·Age: 18 - 45

Code: NCT07703826

The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health

for Preterm Birth

Sponsor: GrowBaby Life Project

Sex: Female·Age: 18+

Code: NCT07559773

Antidepressant Therapy for Improved Blood Vessel Health After Preeclampsia

for Preeclampsia

1 site in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07715669·EARLY_Phase 1

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Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities

for Preterm Birth Complication

1 site in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: Female·Age: 18+

Code: NCT06915428

Progesterone Preeclampsia

for Preeclampsia

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07448597·Phase 4

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

for Hypertension

1 site in Portland

Sponsor: Oregon Health and Science University

Sex: Female·Age: 18+

Code: NCT07293728·Phase 4

Mobile Health Program for Post-Preeclampsia Hypertension

for Hypertension (HTN)

1 site in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 18+

Code: NCT07599579

Advancing Stillbirth Prevention Through Innovative Risk Evaluation (ASPIRE) Clinical Study

for GDM

Sponsor: Medicines360

Sex: Female·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07669935

Mechanistic Underpinnings of Preeclampsia

for Preeclampsia

Sponsor: University of Arizona

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06567899

Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy

for Hypertension, Pregnancy Induced

1 site in Salt Lake City

Sponsor: University of Utah

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05826925

Apply to this trial

Optimizing the Use of Aspirin for the Prevention of Preeclampsia

for Preeclampsia

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Sex: Female·Age: 18+

Code: NCT07665853·Phase 3

Optimizing Preeclampsia Postpartum With Point-of-care Ultrasound

for Preeclampsia

1 site in Orange

Sponsor: University of California, Irvine

Sex: Female·Age: 18+

Code: NCT07167862·Phase 4

Vitamin D Supplementation Among Pregnant Women in Uganda for the Prevention of Hypertensive Disorders in Pregnancy, and Other Adverse Maternal and Foetal Outcomes

for Preeclampsia

Sponsor: St Mary's Hospital, Lacor

Sex: Female·Age: 18+

Code: NCT07510568·Phase 4

Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotension in Preeclamptic Parturients

for Spinal Anesthesia-Induced Hypotension

Sponsor: Ankara City Hospital Bilkent

Sex: Female·Age: 18 - 45

Code: NCT07496788

Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy

for Preeclampsia

2 sites incl. Providence

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT07218237

Apply to this trial

The PreEclampsia Postpartum Prevention Trial

for Preeclampsia

Sponsor: Karolinska Institutet

Sex: Female·Age: 18+

Code: NCT07199283

Apply to this trial

Vagal Stimulation Therapy and Preeclampsia

for Gestational Hypertension

Sponsor: Fundación Internacional René Mey

Sex: Female·Age: 18+

Code: NCT06953115

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Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes

for Type 1 Diabetes

Sponsor: Institut d'Investigacions Biomèdiques August Pi i Sunyer

Sex: Female·Age: 18+

Code: NCT07479329

Kynurenine Concentrations During Pregnancy in Women With or Without Chronic Kidney Disease - A Prospective Multicenter Study

for Chronic Kidney Diseases

Sponsor: CHU de Reims

Sex: Female·Age: 18+

Code: NCT07411937

MitoQ to Improve Vascular Funciton in Preeclampsia

for Preeclampsia

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18 - 50

Code: NCT07229261

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New Therapeutic Strategy Against Preeclampsia

for Preeclampsia

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: Female·Age: 18 - 50

Code: NCT06464159

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Topefilgrastim Injection in the Treatment of High-Risk Pregnant Patients With Preeclampsia

for Preeclampsia

Sponsor: Fang Wang

Sex: Female·Age: 18 - 45

Code: NCT07384936

Evaluation of Patients With Hypertensive Disorders of Pregnancy: An Ambispective Observational Study

for Preeclampsia

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: Female·Age: 18+

Code: NCT07299773

fullPIERS Model in the Prediction of Adverse Maternal Outcomes in Preeclampsia

for Preeclampsia

Sponsor: Sohag University

Sex: Female·Age: All ages

Code: NCT07316140

Cardiometabolic Disease and Substrate Metabolism

for Preeclampsia

1 site in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female·Age: 18 - 45

Code: NCT07565727

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NOPE37: Angiogenic Factors for Managing Term Preeclampsia

for Preeclampsia

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Sex: Female·Age: 18+

Code: NCT07193680

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Effect of Stretching Exercises Versus Aerobic Exercises on Preeclampsia

for Preeclampsia

Sponsor: Cairo University

Sex: Female·Age: 20 - 30

Code: NCT07255677

Effects of Progressive Muscle Relaxation Exercise and Finger Grip Exercise on Stress, Anxiety, Fatigue, Sleep Quality, and Physiological Parameters in Pregnant Women With Preeclampsia

for Pregnancy

Sponsor: Hatice Nur Nefes Pala

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07630623

Cardiovascular Protection After Preeclampsia With Enalapril

for Preeclampsia

Sponsor: Women and Infants Hospital of Rhode Island

Sex: Female·Age: 18+

Code: NCT07222852·Phase 3

Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories

for Preeclampsia

3 sites incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT07041281·Phase 2

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Evaluation of sFlt-1/PlGF Ratio ,OPG and sEng as Predictive Biomarkers in the Diagnosis and Treatment Evaluation of Preeclampsia

for Preeclampsia

Sponsor: Ammar Jassim Abed

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07349277

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AtorvaStatin Postpartum and Reduction of Cardiovascular risK

for Hypertensive Disorders of Pregnancy

1 site in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 20 - 50

Code: NCT06632379·Phase 4

Apply to this trial

Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia

for Pulmonary Edema - Acute

Sponsor: Saint Thomas Hospital, Panama

Sex: Female·Age: All ages

Code: NCT07261956

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Hyperspectral Imaging for Prediction of Preeclampsia

for Preeclampsia (PE) Risk

Sponsor: Heidelberg University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07106294

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Identifying Biomarkers for Endothelial Dysfunction in Women With Preeclampsia

for Endothelial Function (FMD)

Sponsor: University Hospital, Antwerp

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07084727

Apply to this trial

Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

for Preterm Birth

1 site in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16 - 55

Code: NCT06826859·Phase 1, Phase 2

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Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.

for Preeclampsia

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: Female·Age: 18+

Code: NCT06893978

Aspirin 150 mg vs 100 mg for Prevention of Preeclampsia in High-Risk Obese Pregnant Women

for Preeclampsia

Sponsor: FANG HE

Sex: Female·Age: 18 - 45

Code: NCT06952712·Phase 3

Placental Imaging Techniques

for Fetal Growth Restriction (FGR)

1 site in Roanoke

Sponsor: Carilion Clinic

Sex: Female·Age: 18 - 45

Code: NCT06861309

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Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)

for IVF

Sponsor: Aalborg University Hospital

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06471140

A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Participants With Preterm Preeclampsia and Their Children up to 24 Months

for sFlt1 Mediated Preterm Preeclampsia

Sponsor: Comanche Biopharma

Sex: Female·Age: 18 - 45

Code: NCT07282171·Phase 1

Apply to this trial

Exercise Testing After Preeclampsia

for Preeclampsia

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06741436

Apply to this trial

Birth & Breastfeeding Support Study

for Breastfeeding

Sponsor: Herlev Hospital

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06844019

Apply to this trial

Vascular Effects of High-Salt After Preeclampsia

for Preeclampsia

1 site in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06749418·EARLY_Phase 1

Apply to this trial

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

for Preeclampsia

1 site in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: Female·Age: 18 - 45

Code: NCT06802861

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Study of Maternal and Fetal Cardiovascular Function in Hypertensive States of Pregnancy

for Preeclampsia

Sponsor: Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia

Sex: Female·Age: 18+

Code: NCT06858345

Apply to this trial

Association of Urinary Tract Infection With Preeclampsia During Pregnancy

for Urinary Tract Infection (Diagnosis)

Sponsor: Pakistan Air Force (PAF) Hospital Islamabad

Sex: Female·Age: 18 - 35·Accepts healthy volunteers

Code: NCT06962644

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The Effect of Augmented Reality Based Training on Preeclampsia Case

for Preeclampsia

Sponsor: Inonu University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06730048

Probiotic Supplementation During Pregnancy in Women With High-Risk Pregnancies

for Preeclampsia

Sponsor: Region Skane

Sex: Female·Age: 18+

Code: NCT06700044

Apply to this trial

Pilot Project Renal and Cardiovascular Tertiary Prevention in Preeclampsia

for Preeclampsia

Sponsor: University Hospital Schleswig-Holstein

Sex: Female·Age: 18+

Code: NCT07151339

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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

16 sites incl. Birmingham

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4

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Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome

for Fetal Growth Restriction (FGR)

Sponsor: Aristotle University Of Thessaloniki

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06918236

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Assessment of Optic Nerve Sheath Diameter in Preeclamptic Pregnant Women Using Ultrasonography and Anesthetic Management

for Preeclampsia

Sponsor: Kocaeli University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06522295

Feasibility of a Telemonitoring Program for Pregnant Women at High-Risk for Preeclampsia in Pakistan

for Preeclampsia

Sponsor: University Health Network, Toronto

Sex: Female·Age: 18+

Code: NCT05662696

Apply to this trial

Vitamin D3 Supplementation Regimens and Preeclampsia Risk

for Preeclampsia

Sponsor: Sana'a University

Sex: Female·Age: 18 - 40

Code: NCT07648706

Apply to this trial

Preeclampsia clinical trials — common questions

Are preeclampsia clinical trials free to join?

Yes. Participating in a preeclampsia clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a preeclampsia clinical trial?

Each preeclampsia study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a preeclampsia trial near me?

Use the location controls above. We'll show recruiting preeclampsia trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many preeclampsia trials are recruiting right now?

We're currently tracking roughly 25 recruiting preeclampsia trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Preeclampsia trials by city

Birmingham, AL Boston, MA Columbus, OH Aurora, CO Milwaukee, WI Orange, CA Portland, OR Salt Lake City, UT

Related specialties

Women's health Fertility Obstetrics