Clinical Trials at University of North Carolina
As of September 2026, 84 paid clinical trials are recruiting at University of North Carolina, located at 101 MANNING DR, CB 7512, CHAPEL HILL, NC 27514-4220, phone (919) 966-7700 in Chapel Hill, North Carolina. Active studies at this site cover conditions such as Breast Cancer, Multiple Myeloma and Obesity. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Chapel Hill
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
85 clinical trials at University of North Carolina
·Clear filters·A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
US National OCS Heart Perfusion (OHP) Registry
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Total Shoulder Arthroplasty Multi-Center Registry
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children
Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors
Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)
The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia
A Study of NX-1607 in Adults With Advanced Malignancies
Descartes-08 in Autoantibody Myositis
DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma
Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty
How [14C]-DSP-5336 is Absorbed, Broken Down, and Removed From the Body After a Single Oral Dose in Patients With Advanced Blood Cancers
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes
Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
Prospective Evaluation of an AI Diagnostic Ultrasound Tool for Fetal Weight Estimation
IAP-086-1: A Phase 1 Single Ascending Dose First-Time in Human Study
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
Common conditions studied in Chapel Hill
- Breast Cancer (27 active studies)
- Cancer (16 active studies)
- Multiple Myeloma (16 active studies)
- Obesity (11 active studies)
- Ulcerative Colitis (10 active studies)
- Chronic Lymphocytic Leukemia (9 active studies)
Leading research sponsors in Chapel Hill
- University of North Carolina, Chapel Hill
- UNC Lineberger Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Chapel Hill?
There are approximately 692 recruiting clinical trials in Chapel Hill, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chapel Hill pay participants?
Most recruiting trials in Chapel Hill compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chapel Hill?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chapel Hill?
The most common conditions under active study in Chapel Hill include Breast Cancer (27), Cancer (16), Multiple Myeloma (16), Obesity (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chapel Hill?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chapel Hill on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chapel Hill?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chapel Hill?
Recruiting research sites in Chapel Hill include University of North Carolina at Chapel Hill, University of North Carolina, UNC Lineberger Comprehensive Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chapel Hill right now?
The largest active categories in Chapel Hill are Cancer & tumors (241), Diabetes & metabolic (38), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of University of North Carolina?
University of North Carolina is located at 101 MANNING DR, CB 7512, CHAPEL HILL, NC 27514-4220. Use the Google Maps link in the intro above to get directions.
How do I contact University of North Carolina?
You can reach University of North Carolina by phone at (919) 966-7700. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.