Clinical Trials at Duke University Hospital
As of August 2026, 52 paid clinical trials are recruiting at Duke University Hospital, located at 908A ONSLOW ST, DURHAM, NC 27705-4247, phone (203) 376-4428 in Durham, North Carolina. Active studies at this site cover conditions such as Heart Failure, Breast Cancer and Prostate Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Durham
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
53 clinical trials at Duke University Hospital
·Clear filters·Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Strategy for Improving Stroke Treatment Response
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Respiration From Pleth Validation
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
BiVACOR® Total Artificial Heart Early Feasibility Study
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
Development of a Pain Control Options Menu for IUD Insertion
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Pilot Trial for WounDx™ Clinical Decision Support Tool
Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
Photon-counting CT in Chest Imaging
Neuromodulation of Memory in Aging
Anticoagulation in ICH Survivors for Stroke Prevention and Recovery
The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)
Telerehabilitation In The Home After Stroke
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Optimizing Recovery in Trauma Patients by Integrating Enhanced Nutrition Delivery
Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Hyperbaric Oxygen Brain Injury Treatment Trial
Virtual Reality Use for ICU Mobility
Personalized Nutrition to Improve Recovery in Trauma
Repurposing Tilmanocept for Cardiac Sarcoidosis
Common conditions studied in Durham
- Heart Failure (20 active studies)
- Breast Cancer (19 active studies)
- Prostate Cancer (16 active studies)
- Cancer (12 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Stroke (11 active studies)
Leading research sponsors in Durham
- Duke University
- VA Office of Research and Development
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Durham?
There are approximately 1,046 recruiting clinical trials in Durham, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Durham pay participants?
Most recruiting trials in Durham compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Durham?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Durham?
The most common conditions under active study in Durham include Heart Failure (20), Breast Cancer (19), Prostate Cancer (16), Cancer (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Durham?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Durham on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Durham?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Durham?
Recruiting research sites in Durham include Duke University Medical Center, Duke University, Duke University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Durham right now?
The largest active categories in Durham are Cancer & tumors (287), Cardiovascular (95), Neurology & pain (67). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Duke University Hospital?
Duke University Hospital is located at 908A ONSLOW ST, DURHAM, NC 27705-4247. Use the Google Maps link in the intro above to get directions.
How do I contact Duke University Hospital?
You can reach Duke University Hospital by phone at (203) 376-4428. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.