Clinical Trials at Duke Cancer Center Raleigh
As of September 2026, 17 paid clinical trials are recruiting at Duke Cancer Center Raleigh, located at Duke Cancer Center Raleigh, 3404 Wake Forest Rd #100, Raleigh, NC 27609, phone (919) 862-5970 in Raleigh, North Carolina. Active studies at this site cover conditions such as Heart Failure, Coronary Artery Disease and Type 2 Diabetes Mellitus. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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17 clinical trials at Duke Cancer Center Raleigh
·Clear filters·Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
Common conditions studied in Raleigh
- Heart Failure (8 active studies)
- Coronary Artery Disease (5 active studies)
- Type 2 Diabetes Mellitus (5 active studies)
- Obesity (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
Leading research sponsors in Raleigh
- National Cancer Institute (NCI)
- AstraZeneca
- NRG Oncology
- North Carolina State University
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Raleigh?
There are approximately 182 recruiting clinical trials in Raleigh, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Raleigh pay participants?
Most recruiting trials in Raleigh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Raleigh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Raleigh?
The most common conditions under active study in Raleigh include Heart Failure (8), Coronary Artery Disease (5), Type 2 Diabetes Mellitus (5), Obesity (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Raleigh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Raleigh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Raleigh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Raleigh?
Recruiting research sites in Raleigh include Duke Cancer Center Raleigh, Duke Women's Cancer Care Raleigh, WakeMed, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Raleigh right now?
The largest active categories in Raleigh are Cancer & tumors (40), Cardiovascular (21), Diabetes & metabolic (16). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Duke Cancer Center Raleigh?
Duke Cancer Center Raleigh is located at Duke Cancer Center Raleigh, 3404 Wake Forest Rd #100, Raleigh, NC 27609. Use the Google Maps link in the intro above to get directions.
How do I contact Duke Cancer Center Raleigh?
You can reach Duke Cancer Center Raleigh by phone at (919) 862-5970. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.