Paid Clinical Trials in Winston-Salem, NC
As of June 2026, 583 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Winston-Salem offers studies at sites including Wake Forest University Health Sciences for conditions such as Multiple Myeloma, Acute Myeloid Leukemia, Breast Cancer, Malignant Solid Neoplasm. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Winston-Salem
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·Clear filters·↓ Download CSVAbout research studies in Winston-Salem
Winston-Salem has approximately 583 recruiting research studies across a wide range of therapeutic areas. North Carolina hosts Duke University Medical Center, UNC Health, and Wake Forest Baptist Health, with strong programs in oncology, cardiovascular disease, and translational research anchored by Research Triangle Park.
Top Research Study Locations in Winston-Salem
Researchers run research studies in Winston-Salem, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Wake Forest University Health Sciences | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy | 175 |
| Atrium Health Wake Forest Baptist | Aging, Myelofibrosis, Primary Myelofibrosis | 48 |
| Wake Forest University | Amyotrophic Lateral Sclerosis, Heart Failure, Heart Failure With Preserved Ejection Fraction | 27 |
| Wake Forest Baptist Comprehensive Cancer Center | Breast Cancer, Malignant Solid Neoplasm, Nonsmall Cell Lung Cancer Stage III | 23 |
| Novant Health Forsyth Medical Center | Acute Myeloid Leukemia, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 20 |
| Wake Forest Baptist Medical Center | Alzheimer Disease, Ischemic Stroke, Mild Cognitive Impairment | 19 |
| Atrium Health Wake Forest Baptist Comprehensive Cancer Center | Acute Myeloid Leukemia, Cancer, Leukemia, Myeloid, Acute | 16 |
| Wake Forest Baptist Health | Mild Cognitive Impairment, Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia | 15 |
| Atrium Health Wake Forest Baptist Medical Center | Acute Decompensated Heart Failure, Acute Myeloid Leukemias, Amyotrophic Lateral Sclerosis | 12 |
| Southeastern Research Center | Idiopathic Pulmonary Fibrosis (IPF), Progressive Pulmonary Fibrosis, Interstitial Lung Disease | 10 |
| Wake Forest University School of Medicine | Depression, Acute Kidney Injury (AKI), Anesthesia | 10 |
| Wake Forest School of Medicine | Lung Diseases, Acute Respiratory Failure, Bone Loss | 8 |
| Wake Forest University Baptist Medical Center | Amputation, Antibiotic Side Effect, Aortic Stenosis | 6 |
| Wake Forest NCORP Research Base | Breast Carcinoma, Cancer, Colorectal Carcinoma | 6 |
| Novant Health Cancer Institute | Acute Myeloid Leukemia, in Relapse, MDS (Myelodysplastic Syndrome), Acute Myeloid Leukemia Refractory | 5 |
| Wake Forest | Acute Kidney Injury, Anesthesia, Anesthesia Awareness | 5 |
| Wake Forest Baptist | Focal Epilepsy, AAA - Abdominal Aortic Aneurysm, Community-acquired Pneumonia | 4 |
| Wake Forest Health Sciences | Albuminuria, Angiotensin Hypertension, Autonomic Dysfunction | 4 |
| Brookview Hills Research Associates, LLC | Chronic Kidney Disease, Diabetic Kidney Disease (DKD), Kidney Disease | 3 |
| Novant Health | COVID-19, Carcinoma, Non-small-Cell Lung, Colorectal Cancer | 3 |
| Wake Forest University Baptist Health | Androgenic Alopecia, EPP, Gastric Adenocarcinoma | 3 |
| Wake Forest University Health Sciences Department of Dermatology | Dermatologic Disease, ICD10 Code L40.9 for Psoriasis, Psoriasis | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Atrium Health Wake Forest University Health Sciences | Duchenne Muscular Dystrophy, Metastatic Non Small Cell Lung Cancer | 2 |
| Atrium Health-Wake Forest Bapt | Sickle Cell Disease, Thalassemia | 2 |
Active & Upcoming Studies in Winston-Salem (2026)
Recruiting trials in Winston-Salem grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (173 active studies)
- A Phase I Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive ALL · Phase 1 · Wake Forest University Health Sciences
- A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial · Wake Forest University Health Sciences
Neurology & pain (50 active studies)
- Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations · Wake Forest University Health Sciences
- Methadone Pharmacokinetics in Cardiac Surgery · Phase 4 · Wake Forest University Health Sciences
Cardiovascular (29 active studies)
- Tailoring TM-HTN Intervention for Black Patients · Wake Forest University Health Sciences
- BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching · Wake Forest University Health Sciences
Diabetes & metabolic (20 active studies)
- Vibegron for ENergy Thinking and Resilience in Aging · Phase 3 · Wake Forest University Health Sciences
- Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass · Wake Forest University Health Sciences
Mental health & behavior (17 active studies)
- Enhancing Slow Wave Sleep in Depression · Wake Forest University Health Sciences
- Supporting Families in the ICU · Indiana University
Pediatric (8 active studies)
- Comprehensive Care for AYA: Needs Assessment Survey · Wake Forest University Health Sciences
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
Vaccines (6 active studies)
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
- Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses · BioFire Defense LLC
HIV / STI (6 active studies)
- Quitting Matters Human Immunodeficiency Virus Hybrid Trial · Wake Forest University Health Sciences
- Project neuroARTEMIS · Wake Forest University Health Sciences
Eye & vision (3 active studies)
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Common conditions studied in Winston-Salem
- Multiple Myeloma (12 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cancer (11 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Malignant Solid Neoplasm (7 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Chronic Pain (6 active studies). Recruiting Chronic Pain studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Winston-Salem
- Wake Forest University Health Sciences
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- AbbVie
Local regulations and guidelines
Clinical trials in North Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. North Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Winston-Salem. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Winston-Salem
Hipa.ai aggregates every recruiting study in Winston-Salem from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Winston-Salem?
There are approximately 583 recruiting clinical trials in Winston-Salem, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Winston-Salem pay participants?
Most recruiting trials in Winston-Salem compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Winston-Salem?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Winston-Salem?
The most common conditions under active study in Winston-Salem include Multiple Myeloma (12), Cancer (11), Acute Myeloid Leukemia (10), Breast Cancer (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Winston-Salem?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Winston-Salem on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Winston-Salem?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Winston-Salem?
Recruiting research sites in Winston-Salem include Wake Forest University Health Sciences, Atrium Health Wake Forest Baptist, Wake Forest University, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Winston-Salem right now?
The largest active categories in Winston-Salem are Cancer & tumors (173), Neurology & pain (50), Cardiovascular (29). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.