Proteomic Analysis of Patients Undergoing Bariatric Surgery

Sponsor
Universidade Federal de Pernambuco
Study ID
NCT06787807
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • bariatric surgery — PROCEDURE
    sleeve gastrectomy

Study Details

The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery. Therefore, this research aims to better understand protein expression in patients indicated for surgical treatment of obesity, evaluating the pre-operative and post-operative status. The objective of this research is to better understand protein expression in patients indicated for surgical treatment of obesity, evaluating the pre-operative and post-surgery status.

Key Dates

First listed
Jan 22, 2025
Start date
Jun 10, 2025
Status verified
Jan 2025
Primary completion
Sep 9, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
103 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: women with insulin resistance
    An analysis was made of patients with severe steatosis, among patients undergoing bariatric surgery
  • Experimental: patients with severe steatosis
    An analysis was made of patients with severe steatosis, among patients undergoing bariatric surgery
  • Experimental: General patients with insulin resistance
    An analysis was made of patients, among men and women, with insulin resistance, among patients undergoing bariatric surgery
  • Experimental: Patients with above average CRP
    An analysis was carried out of patients with CRP above the average, among patients undergoing bariatric surgery
  • Experimental: Patients with grade 1 obesity
    An analysis was made of patients with grade 1 obesity, among patients undergoing bariatric surgery
  • Experimental: Patients with grade 2 obesity
    An analysis was made of patients with grade 2 obesity, among patients undergoing bariatric surgery
  • Experimental: Patients with grade 3 obesity
    An analysis was made of patients with grade 3 obesity, among patients undergoing bariatric surgery

Primary Outcome Measure

Number of patients with reduced initially upregulated oncogenic proteins [ Time Frame: 1 year after bariatric surgery ]

Central Contacts

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