Oncology Clinical Trials in Raleigh, NC
As of August 2026, 20 paid clinical trials are recruiting for Oncology in Raleigh, North Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
20 clinical trials for Oncology
·Clear filters·Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Registry of Older Patients With Cancer
Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry
Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA
Top Research Study Locations in Raleigh
Researchers run research studies in Raleigh, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke Cancer Center Raleigh | Advanced Hepatocellular Carcinoma, Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate | 17 |
| Duke Women's Cancer Care Raleigh | Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 15 |
| WakeMed | End Stage Renal Disease, Heart Failure, Hemodialysis Access Failure | 11 |
| NC Heart and Vascular Research, LLC | Coronary Artery Disease, Cardiovascular Diseases, Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities | 6 |
| Accellacare of Raleigh | Atherosclerotic Cardiovascular Disease, Chronic Idiopathic Constipation (CIC), Diabetes Mellitus, Type 1 | 5 |
| Duke Raleigh Hospital | Advanced/Metastatic Urothelial Cancer, Atherosclerosis of Extremities, Breast Cancer | 5 |
| WakeMed Health & Hospitals | Intubation Complication, Child Social-Emotional Development, Epigenetic Aging | 5 |
| NC Heart and Vascular Research | Heart Failure, Iliofemoral; Thrombosis, Pulmonary Embolism | 4 |
| North Carolina State University | Alzheimer Disease, Blood Pressure, Diabetes Mellitus Risk | 4 |
| UNC Health Cancer Care Raleigh | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| UNC Health Cancer Care Wakefield | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| Associated Urologists of North Carolina | Benign Prostatic Hyperplasia, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-muscle Invasive Bladder Cancer | 3 |
| NC Heart and Vascular | Carotid Artery Calcification, Carotid Artery Diseases, Coronary Artery Disease | 3 |
| Raleigh Neurology Associates | Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), Multiple Sclerosis, Chronic Inflammatory Demyelinating Polyneuropathy | 3 |
| Accellacare - Raleigh | Atherosclerotic Cardiovascular Disease (ASCVD), Clostridoides Difficile Associated Disease, Elevated Lp(a) | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Care Access | Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes | 2 |
| ClinTrial Research, LLC | Crohn's Disease, Ulcerative Colitis | 2 |
| Duke Women's Cancer Care Raleigh (Pharmacy location and location of CT, MRI and Bone scan machines) | Advanced/Metastatic Urothelial Cancer, Cancer of the Prostate, Hormone Sensitive Prostate Cancer | 2 |
| Eximia Research - NC, LLC | Acute Migraine, Migraine | 2 |
| M3 Wake Research, Inc. | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| NC State University | Diet Interventions, Food Security, Fruit and Vegetable Intake | 2 |
| Rex Healthcare | Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia | 2 |
| TG Therapeutics Investigational Trial Site | Relapsing Multiple Sclerosis, Multiple Sclerosis | 2 |
| US Foot and Ankle Specialists | Diabetic Foot Ulcer (DFU), Lower Extremity, Venous Leg Ulcer (VLU) | 2 |
Active & Upcoming Studies in Raleigh (2026)
Recruiting trials in Raleigh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (40 active studies)
Cardiovascular (21 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation · Biosense Webster, Inc.
Diabetes & metabolic (17 active studies)
- Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study · Endogenex, Inc.
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Neurology & pain (16 active studies)
- Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures · Phase 3 · Rapport Therapeutics Inc.
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Pediatric (2 active studies)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
- Optimizing Tracheal Intubation Outcomes and Neonatal Safety · Children's Hospital of Philadelphia
Mental health & behavior (1 active study)
- A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers · RAI Services Company
Eye & vision (1 active study)
Common conditions studied in Raleigh
- Heart Failure (8 active studies)
- Coronary Artery Disease (5 active studies)
- Type 2 Diabetes Mellitus (5 active studies)
- Obesity (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
Leading research sponsors in Raleigh
- National Cancer Institute (NCI)
- AstraZeneca
- NRG Oncology
- North Carolina State University
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Raleigh?
There are approximately 182 recruiting clinical trials in Raleigh, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Raleigh pay participants?
Most recruiting trials in Raleigh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Raleigh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Raleigh?
The most common conditions under active study in Raleigh include Heart Failure (8), Coronary Artery Disease (5), Type 2 Diabetes Mellitus (5), Obesity (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Raleigh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Raleigh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Raleigh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Raleigh?
Recruiting research sites in Raleigh include Duke Cancer Center Raleigh, Duke Women's Cancer Care Raleigh, WakeMed, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Raleigh right now?
The largest active categories in Raleigh are Cancer & tumors (40), Cardiovascular (21), Diabetes & metabolic (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.