Women's health Clinical Trials in Chapel Hill, NC
As of August 2026, 49 paid clinical trials are recruiting for Women's health in Chapel Hill, North Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Chapel Hill
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
50 clinical trials for Women's health
·Clear filters·A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study of NX-1607 in Adults With Advanced Malignancies
PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients
Prospective Evaluation of an AI Diagnostic Ultrasound Tool for Fetal Weight Estimation
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
Dissemination of BREASTChoice AIM1-B
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Nutrition Awareness Among Women With Non-Metastatic Breast Cancer
The Vanguard Study: Testing a New Way to Screen for Cancer
TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXd
Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
Preoperative Chemotherapy, Pembrolizumab and Low or High Dose RADiation in an Expansion Cohort of Node(+), Triple Negative Breast Cancer
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
A Novel Approach Utilizing Organ Specific Age Proteomics
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
CGM for Management of Type 2 Diabetes in Pregnancy
PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival
Feasibility of Symptom Management for Patients With Metastatic Breast Cancer to Increase Exercise
Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior
Promoting Resilience in Women With Breast Cancer (PRISM -MBC)
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
Menopausal HT for Women Living With HIV (HoT)
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment
Tirzepatide in Obesity-Driven Endometrial Cancer
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
PREDICT-RD: ctDNA Surveillance in TNBC With Residual Disease
Accountability for Care Through Undoing Racism & Equity for Moms
Top Research Study Locations in Chapel Hill
Researchers run research studies in Chapel Hill, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of North Carolina at Chapel Hill | Cancer, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 145 |
| University of North Carolina | Breast Cancer, Metastatic Breast Cancer, Ulcerative Colitis | 96 |
| UNC Lineberger Comprehensive Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 87 |
| The University of North Carolina at Chapel Hill | Hypertension, ACL Tear, AML | 16 |
| UNC Chapel Hill | Lupus Nephritis, Lymphatic Malformations, Barrett's Esophagus | 16 |
| Lineberger Comprehensive Cancer Center | Endometrial Cancer, Adolescent and Young Adult With Brain Cancer, Advanced Solid Tumors | 13 |
| University of North Carolina Chapel Hill | Alport Syndrome, Articular Fractures, Asthma (Diagnosis) | 13 |
| University of North Carolina, Chapel Hill | Hearing Loss, Sensorineural, Acute Myeloid Leukemia (AML), Aging | 11 |
| University of North Carolina Medical Center | Breast Neoplasms, Neoplasm Metastasis, Atrial Fibrillation | 10 |
| UNC Hospitals, The University of North Carolina at Chapel Hill | Cachexia, Melanoma, Cutaneous Malignant, Metastatic Melanoma | 9 |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Breast Cancer, Chronic Myeloproliferative Disorders, Leukemia | 8 |
| University of North Carolina - Chapel Hill | Obstetrical Complications, Ann Arbor Stage I Diffuse Large B-Cell Lymphoma, Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | 8 |
| University of North Carolina at Chapel Hill, Department of Radiation Oncology | Head and Neck Cancer, Sarcoma, Brain Metastases | 7 |
| UNC Hospitals | Acute Respiratory Failure, Comparative Effectiveness, Critical Illness | 6 |
| Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill | Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II | 5 |
| University of North Carolina At Chapel Hill | Chronic Lymphocytic Leukemia, Myeloproliferative Neoplasms, Small Lymphocytic Lymphoma | 5 |
| The University of North Carolina | Breast Cancer, Breast Neoplasms, Kidney Neoplasms | 4 |
| UNC Hospitals, University of North Carolina at Chapel Hill | Acute Myeloid Leukemia, Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With KMT2A Rearrangement | 4 |
| Univeristy of North Carolina at Chapel Hill | Cystic Fibrosis, Drug Induced Liver Injury, Endometrial Cancer | 4 |
| University of North Carolina Hospitals | Carotid Artery Calcification, Carotid Artery Diseases, Gastroschisis | 4 |
| University of North Carolina School of Medicine | Barrett Esophagus, Barretts Esophagus With Dysplasia, Brain Injury | 4 |
| Clinical Trial Site | AQP4+ NMOSD, Generalized Myasthenia Gravis, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 3 |
| North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology | Allergy, Alpha-Gal Syndrome, Peanut Allergy | 3 |
| UNC | Acute Kidney Injury, Chronic Kidney Disease(CKD), Epidemiology | 3 |
| UNC Center for Health Promotion and Disease Prevention | Child Obesity, Down Syndrome, Obesity | 3 |
Active & Upcoming Studies in Chapel Hill (2026)
Recruiting trials in Chapel Hill grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (241 active studies)
- Improving Affordability in Cancer Care Through Economic Screening and Support (I-ACCESS) · UNC Lineberger Comprehensive Cancer Center
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Diabetes & metabolic (38 active studies)
- Optimization of Dietary Adherence in a Mobile Weight Loss Intervention · UNC Lineberger Comprehensive Cancer Center
- Treating Binge Eating and Obesity Digitally in Women · University of North Carolina, Chapel Hill
Cardiovascular (28 active studies)
- A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF · Phase 3 · AstraZeneca
- Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial · Phase 3 · The George Washington University Biostatistics Center
Neurology & pain (19 active studies)
- Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing · University of North Carolina, Chapel Hill
- Neural Mechanisms of Light Driven Analgesia · University of North Carolina, Chapel Hill
Pediatric (16 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Adolescent Mental Health Parenting Program for Child-Adult Relationship Enhancement · University of North Carolina, Chapel Hill
Mental health & behavior (13 active studies)
- Teen Vulnerability to Irritability: Brain and Estrogen Changes · Phase 4 · University of North Carolina, Chapel Hill
- Testing STAR and TextSTAR: A Randomized Controlled Trial · University of Wisconsin, Madison
HIV / STI (10 active studies)
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Characterization of Doxycycline Pharmacokinetics and Adherence · Phase 1 · HIV Prevention Trials Network
Vaccines (4 active studies)
- Woodsmoke Exposure, Influenza Infection, and Nasal Immunity · Phase 4 · University of North Carolina, Chapel Hill
- Long-Term Study of COVID-19 Infection and Long COVID · University of North Carolina, Chapel Hill
Eye & vision (1 active study)
- Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial · University of Pennsylvania
Common conditions studied in Chapel Hill
- Breast Cancer (27 active studies)
- Cancer (16 active studies)
- Multiple Myeloma (16 active studies)
- Obesity (11 active studies)
- Ulcerative Colitis (10 active studies)
- Chronic Lymphocytic Leukemia (9 active studies)
Leading research sponsors in Chapel Hill
- University of North Carolina, Chapel Hill
- UNC Lineberger Comprehensive Cancer Center
- National Cancer Institute (NCI)
- Children's Oncology Group
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Chapel Hill?
There are approximately 692 recruiting clinical trials in Chapel Hill, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Chapel Hill pay participants?
Most recruiting trials in Chapel Hill compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Chapel Hill?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Chapel Hill?
The most common conditions under active study in Chapel Hill include Breast Cancer (27), Cancer (16), Multiple Myeloma (16), Obesity (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Chapel Hill?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Chapel Hill on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Chapel Hill?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Chapel Hill?
Recruiting research sites in Chapel Hill include University of North Carolina at Chapel Hill, University of North Carolina, UNC Lineberger Comprehensive Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Chapel Hill right now?
The largest active categories in Chapel Hill are Cancer & tumors (241), Diabetes & metabolic (38), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.