Women's health Clinical Trials in Durham, NC
As of August 2026, 40 paid clinical trials are recruiting for Women's health in Durham, North Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Durham
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
41 clinical trials for Women's health
·Clear filters·A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
A Study of PHST001 in Advanced Solid Tumors
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
Identifying Patterns in the Breath of Individuals With Breast Cancer
A Study of a Decision Tool for People Considering Breast Reconstruction Surgery
Behavioral Pain Intervention for Older Cancer Patients
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer
Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs
Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors
SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers
Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery
Cervical Cancer Detection Using Optical Spectroscopy
Pilot Study for Speculum Free Cervical Cancer Screening
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
Symptom Management and Transitioning to Engagement With Post-treatment Care for Adolescent and Young Adult Cancer Survivors
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
PRospective Evaluation of Peripartum Anticoagulation ManaGement for ThrOmboembolism
Weight Management After Cancer for Survivors in Rural Communities
DESTINY-PANTUMOUR04
Planning Grant for TOPS for Breast Cancer Survivors
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
Top Research Study Locations in Durham
Researchers run research studies in Durham, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke University Medical Center | Acute Myeloid Leukemia, Pulmonary Arterial Hypertension, Sickle Cell Disease | 279 |
| Duke University | Heart Failure, Prostate Cancer, Breast Cancer | 199 |
| Duke University Hospital | Heart Failure, Stroke, Traumatic Brain Injury | 58 |
| Duke University Health System | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 46 |
| Duke Cancer Institute | Breast Cancer, Advanced Solid Tumor, Cancer | 39 |
| Duke Cancer Center | Advanced Solid Tumor, Breast Cancer, Non-small Cell Lung Cancer | 32 |
| Durham VA Medical Center, Durham, NC | Tobacco Use Disorder, Cancer, Hearing Loss | 32 |
| Durham VA Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 17 |
| Duke University School of Medicine | Accidental Falls/Prevention and Control, Acquired Resistance to KRAS G12C Inhibitor, Acute Respiratory Failure | 14 |
| Duke Eye Center | Geographic Atrophy, Stargardt Disease, Age - Related Macular Degeneration (AMD) | 12 |
| Duke University Eye Center | Amblyopia, Retinal Disease, Eye Diseases | 12 |
| Duke Vaccine and Trials Unit | COVID -19, COVID-19 Infection, COVID-19 Vaccines | 7 |
| Duke University - Main Hospital and Clinics | Advanced Hepatocellular Carcinoma, COVID-19 Infection, Carcinoma, Hepatocellular | 6 |
| Clinical Trial Site | ATTR Amyloidosis, Cutaneous Sarcoidosis, Generalized Myasthenia Gravis | 6 |
| Duke Health | Breast Reconstruction, Cancer, Congestive Heart Failure Chronic | 6 |
| Duke University Medical Center - Duke Cancer Center | Advanced Solid Tumor, Cancer of the Prostate, Colorectal Cancer | 6 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Colonic Neoplasms, HIV Infections | 6 |
| Duke Children's Hospital | Adamantinomatous Craniopharyngioma, Becker Muscular Dystrophy, Cardiomyopathy | 5 |
| Duke | Advanced Ovarian Carcinoma, Chronic Graft Versus Host Disease, Chronic Kidney Diseases | 4 |
| Duke Cancer Network | Advanced Breast Cancer, Advanced Colorectal Adenocarcinoma, Advanced Colorectal Carcinoma | 4 |
| Duke Children's Hospital & Health Center | Analgesics, Opioid, Congenital Heart Disease (CHD), Dravet Syndrome | 4 |
| Duke Lung Transplant Clinic - Clinic 2F/2G - PPDS | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| Duke Regional Hospital | Agitated Delirium, Atherosclerosis of Extremities, Delirium Confusional State | 4 |
| RTI International | Alcohol Misuse, Bystander Intervention, Community Reintegration | 4 |
| Duke Blood Cancer Center | AML With Mutated NPM1, Acute Myeloid Leukemia, Acute Myeloid Leukemia Recurrent | 3 |
Active & Upcoming Studies in Durham (2026)
Recruiting trials in Durham grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (286 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- ORASIS in Breast Reconstruction · Duke University
Cardiovascular (95 active studies)
Neurology & pain (67 active studies)
Diabetes & metabolic (32 active studies)
- Studies of Insulin and Glucagon Action in the Liver · Phase 1, Phase 2 · Duke University
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Pediatric (26 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Building Relationship, Improving Dialogue, and Growing Empathy (BRIDGE): An Intervention to Support Decision Making for Critically Ill Children · Duke University
Mental health & behavior (22 active studies)
- Abstinence Reinforcement Therapy for Veterans Who Smoke Tobacco and Are Experiencing Homelessness · VA Office of Research and Development
- Pilot Feasibility Study With Doulas · Duke University
HIV / STI (13 active studies)
Eye & vision (11 active studies)
- Advancing Pediatric Retinal Imaging With Auto-aligned OCT · Duke University
- Automated Applanation Tonometry - Updated · Duke University
Vaccines (9 active studies)
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age · Phase 4 · BioNTech SE
Common conditions studied in Durham
- Heart Failure (20 active studies)
- Breast Cancer (19 active studies)
- Prostate Cancer (16 active studies)
- Cancer (12 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Stroke (11 active studies)
Leading research sponsors in Durham
- Duke University
- VA Office of Research and Development
- National Cancer Institute (NCI)
- AstraZeneca
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in Durham?
There are approximately 1,045 recruiting clinical trials in Durham, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Durham pay participants?
Most recruiting trials in Durham compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Durham?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Durham?
The most common conditions under active study in Durham include Heart Failure (20), Breast Cancer (19), Prostate Cancer (16), Cancer (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Durham?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Durham on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Durham?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Durham?
Recruiting research sites in Durham include Duke University Medical Center, Duke University, Duke University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Durham right now?
The largest active categories in Durham are Cancer & tumors (286), Cardiovascular (95), Neurology & pain (67). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.