Paid Clinical Trials in Raleigh, NC
As of July 2026, 183 paid clinical trials are recruiting in Raleigh, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Raleigh offers studies at sites including Duke Cancer Center Raleigh for conditions such as Heart Failure, Coronary Artery Disease, Type 2 Diabetes Mellitus, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Raleigh
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·Clear filters·Top Research Study Locations in Raleigh
Researchers run research studies in Raleigh, NC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Duke Cancer Center Raleigh | Advanced Hepatocellular Carcinoma, Cancer of the Prostate, Carcinoma, Hepatocellular | 16 |
| Duke Women's Cancer Care Raleigh | Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 15 |
| WakeMed | End Stage Renal Disease, Heart Failure, Hemodialysis Access Failure | 10 |
| Accellacare of Raleigh | Obesity, Overweight, Atherosclerotic Cardiovascular Disease | 6 |
| NC Heart and Vascular Research, LLC | Coronary Artery Disease, Cardiovascular Diseases, Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities | 6 |
| NC Heart and Vascular Research | Heart Failure, Iliofemoral; Thrombosis, Pulmonary Embolism | 5 |
| WakeMed Health & Hospitals | Intubation Complication, Child Social-Emotional Development, Epigenetic Aging | 5 |
| Duke Raleigh Hospital | Atherosclerosis of Extremities, Breast Cancer, Breast Reconstruction | 4 |
| North Carolina State University | Alzheimer Disease, Blood Pressure, Diabetes Mellitus Risk | 4 |
| UNC Health Cancer Care Raleigh | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| UNC Health Cancer Care Wakefield | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 4 |
| Raleigh Neurology Associates | Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic | 4 |
| Associated Urologists of North Carolina | Benign Prostatic Hyperplasia, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Non-muscle Invasive Bladder Cancer With Carcinoma in Situ | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Care Access | Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes | 2 |
| ClinTrial Research, LLC | Crohn's Disease, Ulcerative Colitis | 2 |
| Eximia Research - NC, LLC | Acute Migraine, Migraine | 2 |
| M3 Wake Research, Inc. | Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| NC Heart and Vascular | Coronary Artery Disease, Hypertension | 2 |
| NC State University | Diet Interventions, Food Security, Fruit and Vegetable Intake | 2 |
| North Carolina Nephrology, PA | End Stage Kidney Disease, Primary IgA Nephropathy | 2 |
| Rex Healthcare | Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia | 2 |
| TG Therapeutics Investigational Trial Site | Relapsing Multiple Sclerosis, Multiple Sclerosis | 2 |
| US Foot and Ankle Specialists | Diabetic Foot Ulcer (DFU), Lower Extremity, Venous Leg Ulcer (VLU) | 2 |
| Velocity Clinical Research | Epilepsy, Focal Epilepsy, Focal Seizure | 2 |
Active & Upcoming Studies in Raleigh (2026)
Recruiting trials in Raleigh grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (39 active studies)
Cardiovascular (20 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation · Biosense Webster, Inc.
Neurology & pain (19 active studies)
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Diabetes & metabolic (16 active studies)
Mental health & behavior (2 active studies)
- A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers · RAI Services Company
- Effect of Flavored on!® Nicotine Pouch Products on Smoking Behaviors: a SMART Study · Altria Client Services LLC
Pediatric (2 active studies)
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
- Optimizing Tracheal Intubation Outcomes and Neonatal Safety · Children's Hospital of Philadelphia
Common conditions studied in Raleigh
- Heart Failure (8 active studies)
- Coronary Artery Disease (5 active studies)
- Type 2 Diabetes Mellitus (4 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
- Crohn's Disease (3 active studies)
Leading research sponsors in Raleigh
- National Cancer Institute (NCI)
- AstraZeneca
- North Carolina State University
- NRG Oncology
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Raleigh?
There are approximately 183 recruiting clinical trials in Raleigh, North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Raleigh pay participants?
Most recruiting trials in Raleigh compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Raleigh?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Raleigh?
The most common conditions under active study in Raleigh include Heart Failure (8), Coronary Artery Disease (5), Type 2 Diabetes Mellitus (4), Anatomic Stage II Breast Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Raleigh?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Raleigh on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Raleigh?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Raleigh?
Recruiting research sites in Raleigh include Duke Cancer Center Raleigh, Duke Women's Cancer Care Raleigh, WakeMed, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Raleigh right now?
The largest active categories in Raleigh are Cancer & tumors (39), Cardiovascular (20), Neurology & pain (19). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.